Christopher Barrington
Overview
Explore the profile of Christopher Barrington including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
690
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0
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Recent Articles
1.
Guerin T, Barrington C, Pobegalov G, Molodtsov M, Uhlmann F
EMBO J
. 2025 Jan;
44(5):1563-1568.
PMID: 39890887
No abstract available.
2.
Saag L, Utevska O, Zadnikov S, Shramko I, Gorbenko K, Bandrivskyi M, et al.
Sci Adv
. 2025 Jan;
11(2):eadr0695.
PMID: 39772694
The North Pontic region, which encompasses present-day Ukraine, was a crossroads of migration, connecting the vast Eurasian Steppe with Central Europe. We generated shotgun-sequenced genomic data for 91 individuals dating...
3.
Speidel L, Silva M, Booth T, Raffield B, Anastasiadou K, Barrington C, et al.
Nature
. 2025 Jan;
637(8044):118-126.
PMID: 39743601
Many known and unknown historical events have remained below detection thresholds of genetic studies because subtle ancestry changes are challenging to reconstruct. Methods based on shared haplotypes and rare variants...
4.
Guerin T, Barrington C, Pobegalov G, Molodtsov M, Uhlmann F
EMBO J
. 2024 Aug;
43(19):4173-4196.
PMID: 39160275
The ring-shaped cohesin complex topologically entraps two DNA molecules to establish sister chromatid cohesion. Cohesin also shapes the interphase chromatin landscape with wide-ranging implications for gene regulation, and cohesin is...
5.
Dietzen M, Zhai H, Lucas O, Pich O, Barrington C, Lu W, et al.
Nat Commun
. 2024 Jul;
15(1):6039.
PMID: 39019871
During each cell cycle, the process of DNA replication timing is tightly regulated to ensure the accurate duplication of the genome. The extent and significance of alterations in this process...
6.
Anastasiadou K, Silva M, Booth T, Speidel L, Audsley T, Barrington C, et al.
Commun Biol
. 2024 Jan;
7(1):14.
PMID: 38212558
Ancient DNA is a valuable tool for investigating genetic and evolutionary history that can also provide detailed profiles of the lives of ancient individuals. In this study, we develop a...
7.
Silva M, Booth T, Moore J, Anastasiadou K, Walker D, Gilardet A, et al.
Curr Biol
. 2023 Dec;
34(1):204-212.e6.
PMID: 38118448
In the second century CE the Roman Empire had increasing contact with Sarmatians, nomadic Iranian speakers occupying an area stretching from the Pontic-Caspian steppe to the Carpathian mountains, both in...
8.
Cooke C, Barrington C, Baillie-Benson P, Nichols J, Moris N
Development
. 2023 Aug;
150(17).
PMID: 37526602
Primordial germ cells (PGCs) are the early embryonic precursors of gametes - sperm and egg cells. PGC-like cells (PGCLCs) can currently be derived in vitro from pluripotent cells exposed to...
9.
Lopez-Rodriguez J, Hancock S, Li K, Crotta S, Barrington C, Suarez-Bonnet A, et al.
J Exp Med
. 2023 Jul;
220(10).
PMID: 37516912
Mucosal-associated invariant T (MAIT) cells are abundant in the lung and contribute to host defense against infections. During bacterial infections, MAIT cell activation has been proposed to require T cell...
10.
Brookes E, Martinez De La Cruz B, Boulasiki P, Au H, Varsally W, Barrington C, et al.
iScience
. 2022 Dec;
26(1):105695.
PMID: 36582820
Brain-derived neurotrophic factor (BDNF) promotes neuronal differentiation and survival and is implicated in the pathogenesis of many neurological disorders. Here, we identified a novel intergenic enhancer located 170 kb from...