Christopher A Ross
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Explore the profile of Christopher A Ross including associated specialties, affiliations and a list of published articles.
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Articles
237
Citations
14970
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Recent Articles
11.
Zandi P, Jaffe A, Goes F, Burke E, Collado-Torres L, Huuki-Myers L, et al.
Nat Neurosci
. 2022 Mar;
25(3):381-389.
PMID: 35260864
Recent genetic studies have identified variants associated with bipolar disorder (BD), but it remains unclear how brain gene expression is altered in BD and how genetic risk for BD may...
12.
Ratovitski T, Jiang M, OMeally R, Rauniyar P, Chighladze E, Farago A, et al.
Hum Mol Genet
. 2021 Dec;
31(10):1651-1672.
PMID: 34888656
Huntington's disease (HD) is an incurable neurodegenerative disorder caused by a CAG expansion in the huntingtin gene (HTT). Post-translational modifications of huntingtin protein (HTT), such as phosphorylation, acetylation and ubiquitination,...
13.
Zhang J, Li K, Wang X, Smith A, Ning B, Liu Z, et al.
Front Aging Neurosci
. 2021 Nov;
13:754956.
PMID: 34720999
Mutations in () are the most frequent genetic factors contributing to Parkinson's disease (PD). G2385R- increases the risk for PD susceptibility in the Chinese population. However, the pathological role of...
14.
Benatar M, Wuu J, McHutchison C, Postuma R, Boeve B, Petersen R, et al.
Brain
. 2021 Oct;
145(1):27-44.
PMID: 34677606
Significant progress has been made in understanding the pre-symptomatic phase of amyotrophic lateral sclerosis. While much is still unknown, advances in other neurodegenerative diseases offer valuable insights. Indeed, it is...
15.
Li P, Moulick R, Feng H, Sun X, Arbez N, Jin J, et al.
Mov Disord
. 2021 Aug;
36(11):2519-2529.
PMID: 34390268
Background: Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease caused by expansion of a CAG repeat in Ataxin-2 (ATXN2) gene. The mutant ATXN2 protein with a polyglutamine tract is...
16.
Akimov S, Jiang M, Kedaigle A, Arbez N, Marque L, Eddings C, et al.
Hum Mol Genet
. 2021 Jul;
30(24):2469-2487.
PMID: 34296279
We have previously established induced pluripotent stem cell (iPSC) models of Huntington's disease (HD), demonstrating CAG-repeat-expansion-dependent cell biological changes and toxicity. However, the current differentiation protocols are cumbersome and time...
17.
Liu H, Zhang C, Xu J, Jin J, Cheng L, Miao X, et al.
Brain
. 2021 May;
144(10):3101-3113.
PMID: 34043007
Huntington's disease is a dominantly inherited, fatal neurodegenerative disorder caused by a CAG expansion in the huntingtin (HTT) gene, coding for pathological mutant HTT protein (mHTT). Because of its gain-of-function...
18.
Wang X, Guo G, Zhang J, Aebez N, Liu Z, Liu C, et al.
Hum Mol Genet
. 2021 May;
30(16):1535-1542.
PMID: 34002226
Parkinson's disease (PD) is a neurodegenerative disease with movement disorders including resting tremor, rigidity, bradykinesia and postural instability. Recent studies have identified a new PD associated gene, TMEM230 (transmembrane protein...
19.
Kim N, Wen Z, Liu J, Zhou Y, Guo Z, Xu C, et al.
Nat Commun
. 2021 May;
12(1):2570.
PMID: 33931639
No abstract available.
20.
Migazzi A, Scaramuzzino C, Anderson E, Tripathy D, Hernandez I, Grant R, et al.
Cell Rep
. 2021 Apr;
35(2):108980.
PMID: 33852844
The huntingtin (HTT) protein transports various organelles, including vesicles containing neurotrophic factors, from embryonic development throughout life. To better understand how HTT mediates axonal transport and why this function is...