Christophe Bosc
Overview
Explore the profile of Christophe Bosc including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
40
Citations
1198
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ma D, Sun C, Manne R, Guo T, Bosc C, Barry J, et al.
Mol Psychiatry
. 2023 Oct;
28(9):3994-4010.
PMID: 37833406
The pathogenesis of schizophrenia is believed to involve combined dysfunctions of many proteins including microtubule-associated protein 6 (MAP6) and Kv3.1 voltage-gated K (Kv) channel, but their relationship and functions in...
2.
Ramirez-Rios S, Choi S, Sanyal C, Blum T, Bosc C, Krichen F, et al.
J Cell Biol
. 2022 Dec;
222(2).
PMID: 36512346
The detyrosination/tyrosination cycle of α-tubulin is critical for proper cell functioning. VASH1-SVBP and VASH2-SVBP are ubiquitous enzymes involved in microtubule detyrosination, whose mode of action is little known. Here, we...
3.
Peris L, Parato J, Qu X, Soleilhac J, Lante F, Kumar A, et al.
Brain
. 2022 Feb;
145(7):2486-2506.
PMID: 35148384
Microtubules play fundamental roles in the maintenance of neuronal processes and in synaptic function and plasticity. While dynamic microtubules are mainly composed of tyrosinated tubulin, long-lived microtubules contain detyrosinated tubulin,...
4.
Boulan B, Ravanello C, Peyrel A, Bosc C, Delphin C, Appaix F, et al.
Elife
. 2021 Dec;
10.
PMID: 34860155
Neurodevelopmental axonal pathfinding plays a central role in correct brain wiring and subsequent cognitive abilities. Within the growth cone, various intracellular effectors transduce axonal guidance signals by remodeling the cytoskeleton....
5.
Cuveillier C, Boulan B, Ravanello C, Denarier E, Deloulme J, Gory-Faure S, et al.
Front Mol Neurosci
. 2021 May;
14:665693.
PMID: 34025352
The development and function of the central nervous system rely on the microtubule (MT) and actin cytoskeletons and their respective effectors. Although the structural role of the cytoskeleton has long...
6.
Moutin M, Bosc C, Peris L, Andrieux A
Dev Neurobiol
. 2020 Dec;
81(3):253-272.
PMID: 33325152
Microtubules (MTs) are an essential component of the neuronal cytoskeleton; they are involved in various aspects of neuron development, maintenance, and functions including polarization, synaptic plasticity, and transport. Neuronal MTs...
7.
Cuveillier C, Delaroche J, Seggio M, Gory-Faure S, Bosc C, Denarier E, et al.
Sci Adv
. 2020 Apr;
6(14):eaaz4344.
PMID: 32270043
Neuronal activities depend heavily on microtubules, which shape neuronal processes and transport myriad molecules within them. Although constantly remodeled through growth and shrinkage events, neuronal microtubules must be sufficiently stable...
8.
Pagnamenta A, Heemeryck P, Martin H, Bosc C, Peris L, Uszynski I, et al.
Hum Mol Genet
. 2019 Aug;
28(20):3391-3405.
PMID: 31363758
Reversible detyrosination of tubulin, the building block of microtubules, is crucial for neuronal physiology. Enzymes responsible for detyrosination were recently identified as complexes of vasohibins (VASHs) one or two with...
9.
Wang N, Bosc C, Choi S, Boulan B, Peris L, Olieric N, et al.
Nat Struct Mol Biol
. 2019 Jun;
26(7):571-582.
PMID: 31235911
Vasohibins are tubulin tyrosine carboxypeptidases that are important in neuron physiology. We examined the crystal structures of human vasohibin 1 and 2 in complex with small vasohibin-binding protein (SVBP) in...
10.
Giordano T, Gadadhar S, Bodakuntla S, Straub J, Leboucher S, Martinez G, et al.
J Cell Sci
. 2019 Jan;
132(3).
PMID: 30635446
Sperm cells are highly specialized mammalian cells, and their biogenesis requires unique intracellular structures. Perturbation of spermatogenesis often leads to male infertility. Here, we assess the role of a post-translational...