Christine M Komarck
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Explore the profile of Christine M Komarck including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
481
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0
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Recent Articles
1.
Zhang H, Kim S, Chen Z, Nannapaneni S, Chen A, Moore C, et al.
Head Neck
. 2017 Sep;
39(12):2433-2443.
PMID: 28945296
Background: We examined the prognostic value of a panel of biomarkers in patients with squamous cell carcinoma of the head and neck (SCCHN) who were human immunodeficiency virus (HIV) positive...
2.
Owen J, Komarck C, Wang A, Abuzeid W, Keep R, McKean E, et al.
J Neurosurg
. 2017 Apr;
128(3):701-709.
PMID: 28430034
OBJECTIVE Chordomas are rare malignant tumors thought to arise from remnants of the notochord. They can be located anywhere along the axial skeleton but are most commonly found in the...
3.
Genomic Integration of High-Risk HPV Alters Gene Expression in Oropharyngeal Squamous Cell Carcinoma
Walline H, Komarck C, McHugh J, Bellile E, Brenner J, Prince M, et al.
Mol Cancer Res
. 2016 Jul;
14(10):941-952.
PMID: 27422711
Implications: Integration of transcriptionally active hrHPV into cellular intergenic regions associates with tumor behavior by altering gene expression. Mol Cancer Res; 14(10); 941-52. ©2016 AACR.
4.
Rudy S, Brenner J, Harris J, Liu J, Che J, Scott M, et al.
J Otolaryngol Head Neck Surg
. 2016 Apr;
45:26.
PMID: 27117272
Background: Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer with poor overall survival. New therapeutic strategies that target specific molecular lesions driving advanced disease are needed. Herein...
5.
Birkeland A, Yanik M, Tillman B, Scott M, Foltin S, Mann J, et al.
JAMA Otolaryngol Head Neck Surg
. 2016 Apr;
142(6):559-67.
PMID: 27077364
Importance: ERBB2 (formerly HER2) is an important drug target in breast cancer, where anti-ERBB2 therapy has been shown to lead to improvements in disease recurrence and overall survival. ERBB2 status...
6.
Scheel A, Lin G, McHugh J, Komarck C, Walline H, Prince M, et al.
Int Forum Allergy Rhinol
. 2015 Jun;
5(8):701-7.
PMID: 26077310
Background: The role of human papillomavirus (HPV) in sinonasal inverted papillomas (IPs) is controversial. Determining the prevalence of HPV infection and its impact on the molecular biology of these tumors...
7.
Madera D, Vitale-Cross L, Martin D, Schneider A, Molinolo A, Gangane N, et al.
Cancer Prev Res (Phila)
. 2015 Feb;
8(3):197-207.
PMID: 25681087
Most squamous cell carcinomas of the head and neck (HNSCC) exhibit a persistent activation of the PI3K-mTOR signaling pathway. We have recently shown that metformin, an oral antidiabetic drug that...
8.
Vainshtein J, McHugh J, Spector M, Walline H, Komarck C, Stenmark M, et al.
Head Neck
. 2014 Jun;
37(1):8-11.
PMID: 24962247
Background: Although typically associated with a favorable prognosis, a minority of human papillomavirus (HPV)-related (+) oropharyngeal cancers recur after chemoradiation. We postulated that a minor HPV-negative tumor subfraction may be...
9.
Vainshtein J, Spector M, McHugh J, Wong K, Walline H, Byrd S, et al.
Oral Oncol
. 2014 Feb;
50(5):513-9.
PMID: 24565983
Background: To determine whether the addition of molecular and imaging biomarkers to established clinical risk factors could help predict locoregional failure (LRF) after chemoradiation in human papillomavirus (HPV)-related (+) oropharyngeal...
10.
Maine G, Mao X, Muller P, Komarck C, Klomp L, Burstein E
Biochem J
. 2008 Sep;
417(2):601-9.
PMID: 18795889
COMMD {COMM [copper metabolism Murr1 (mouse U2af1-rs1 region 1)] domain-containing} proteins participate in several cellular processes, ranging from NF-kappaB (nuclear factor kappaB) regulation, copper homoeostasis, sodium transport and adaptation to...