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Christine E Sheehan

Explore the profile of Christine E Sheehan including associated specialties, affiliations and a list of published articles. Areas
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Articles 42
Citations 1897
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Recent Articles
1.
Day T, Kallakury B, Ross J, Voronel O, Vaidya S, Sheehan C, et al.
Mol Cancer Res . 2019 Jan; 17(5):1207-1219. PMID: 30647104
Aberrant regulation of EGFR is common in non-small cell lung carcinomas (NSCLC), and tumor resistance to targeted therapies has been attributed to emergence of other co-occurring oncogenic events, parallel bypass...
2.
Lee H, Fu Z, Koo B, Sheehan C, Young G, Lin J, et al.
Ann Diagn Pathol . 2018 Sep; 37:30-34. PMID: 30236546
Background: The expression profile of immunohistochemical markers of origin in poorly differentiated neuroendocrine carcinoma (PDNEC) is not well studied. Materials And Methods: Seventy-four PDNECs from gastroenteropancreatic (GEP) organs and the...
3.
Fu Z, Zuo C, Sheehan C, Patil D, Lin J, Yang Z, et al.
Appl Immunohistochem Mol Morphol . 2018 Mar; 27(6):454-460. PMID: 29561272
Although nuclear immunostaining for paired box protein (PAX5) is widely used in practice, its cytoplasmic localization has not been evaluated. Recently we encountered cytoplasmic granular PAX5 staining in rectal well-differentiated...
4.
Najjar S, Ahn S, Kasago I, Zuo C, Umrau K, Ainechi S, et al.
Eur J Pediatr Surg . 2018 Jan; 29(2):179-187. PMID: 29304518
Purpose:  Quantification of calretinin-stained mucosal nerve fibers by image processing and analysis (IPA) may objectively define the transition zone (TZ) of Hirschsprung disease (HD). We tested the utility of IPA...
5.
Abdul Karim L, Kallakury B, Chahine J, Sheehan C, Ross J
Appl Immunohistochem Mol Morphol . 2017 Dec; 26(2):e22. PMID: 29189261
No abstract available.
6.
Ross J, Ali S, Fasan O, Block J, Pal S, Elvin J, et al.
Oncologist . 2017 Oct; 22(12):1444-1450. PMID: 29079636
Background: Genomic fusions of the anaplastic lymphoma kinase gene () are a well-established therapy target in non-small cell lung cancer (NSCLC). From a survey of 114,200 clinical cases, we determined...
7.
Jabbour T, Ross J, Sheehan C, Affolter K, Geiersbach K, Boguniewicz A, et al.
J Clin Pathol . 2017 Jul; 71(1):46-51. PMID: 28667193
Aims: Routine application of PD-L1 immunohistochemistry (IHC) in colorectal cancer (CRC) is limited due to lack of standardized scoring criteria, antibody clones, and intratumoral staining heterogeneity. We assessed PD-L1 protein...
8.
Nozad S, Sheehan C, Gay L, Elvin J, Vergilio J, Suh J, et al.
Breast Cancer Res Treat . 2017 Feb; 162(3):597-602. PMID: 28210881
Purpose: Malignant phyllodes tumors (MPT) are exceptionally rare, and the genomic drivers of these tumors are still being elucidated. We performed comprehensive genomic profiling (CGP) of MPT to identify genomic...
9.
Carlson J, Xavier Jr J, Tarasen A, Sheehan C, Otto G, Miller V, et al.
Am J Dermatopathol . 2017 Jan; 39(1):1-13. PMID: 28045747
Background: Comprehensive genomic profiling of clinical samples by next-generation sequencing (NGS) can identify one or more therapy targets for the treatment of metastatic melanoma (MM) with a single diagnostic test....
10.
Ainechi S, Mann S, Lin J, Patil D, Sheehan C, Yang Z, et al.
Appl Immunohistochem Mol Morphol . 2016 Dec; 26(8):545-551. PMID: 27941564
Paired Box 5 (PAX5), a well-established B-cell marker, is preferentially expressed in small cell lung carcinoma and regulates the transcription of c-Met, offering a potential for therapeutic target. Its expression...