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Christian K Vorwerk

Explore the profile of Christian K Vorwerk including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 259
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Recent Articles
1.
Vorwerk C, Tuchen S, Streit F, Binder L, Hofmuller W, Behrens-Baumann W
Ophthalmic Res . 2009 Jan; 41(2):102-5. PMID: 19122472
Background: The echinocandin caspofungin (CAS) is a novel antifungal drug with fungicidal in vitro activity against all Candida spp., which are the most frequent cause of fungal keratitis. Penetration of...
2.
Vorwerk C, Streit F, Binder L, Tuchen S, Knop C, Behrens-Baumann W
Graefes Arch Clin Exp Ophthalmol . 2008 May; 246(8):1179-83. PMID: 18491124
Objectives: Voriconazol is a triazole antifungal drug with in vitro fungicidal activity against all Candida spp., Fusarium spp. and Aspergillus spp. which are frequent causes of fungal keratitis depending on...
3.
Mawrin C, Schulz S, Hellwig-Patyk A, Kirches E, Roessner A, Lendeckel U, et al.
J Neuropathol Exp Neurol . 2005 Dec; 64(12):1080-8. PMID: 16319718
Although somatostatin receptors have been detected in many normal and neoplastic tissues, little is known of their expression and function in peripheral nerve tumors. In the present study, we examined...
4.
Mawrin C, Kirches E, Diete S, Wiedemann F, Schneider T, Firsching R, et al.
Cancer Lett . 2005 Oct; 239(2):239-45. PMID: 16198476
The FGFR4 codon 388 polymorphism (Arg(388), Arg/Gly(388) or Gly(388)) was determined in glioblastoma multiforme (GBM), anaplastic astrocytomas (AA), diffuse astrocytomas (DA), and control muscles. Arg(388) was rare in AA, GBM,...
5.
Mawrin C, Sasse T, Kirches E, Kropf S, Schneider T, Grimm C, et al.
Clin Cancer Res . 2005 Jun; 11(11):4074-82. PMID: 15930342
Purpose: Activation of intracellular signaling cascades has been implicated in the growth control of benign meningiomas, but their role for meningioma progression and outcome is unknown. Here we determined the...
6.
Mawrin C, von Mawrin A, Kirches E, Schneider-Stock R, Boltze C, Vorwerk C, et al.
J Neurooncol . 2005 Jun; 72(2):115-22. PMID: 15925990
Gliomatosis cerebri (GC) is regarded as a rare glial neoplasm of unknown origin, and a detailed analysis of molecular alterations underlying this disease has started only recently. However, because GC...
7.
Stix B, Leber M, Bingemer P, Gross C, Ruschoff J, Fandrich M, et al.
Invest Ophthalmol Vis Sci . 2005 Mar; 46(4):1133-9. PMID: 15790870
Purpose: To investigate the molecular basis of hereditary lattice corneal dystrophy (LCD) type IIIA associated with corneal amyloid deposits afflicting several members of a four-generation family. Methods: Histologic, immunohistochemical and...
8.
Mawrin C, Kirches E, Krause G, Wiedemann F, Vorwerk C, Bogerts B, et al.
Neuroreport . 2004 Apr; 15(6):939-43. PMID: 15076711
One possible cause for the neuronal loss in sporadic amyotrophic lateral sclerosis (S-ALS) is an increase of free radicals, which may produce oxidative damage to susceptible biomolecules, which, in turn,...
9.
Mawrin C, Kirches E, Krause G, Schneider-Stock R, Bogerts B, Vorwerk C, et al.
Neurosci Lett . 2004 Mar; 357(2):111-4. PMID: 15036587
Mitochondrial dysfunction caused by mitochondrial DNA (mtDNA) aberrations has been implicated in the neuronal death in neurodegenerative disorders. Significant neuronal damage can occur if the percentage of mtDNA mutations may...
10.
Vorwerk C, Zurakowski D, McDermott L, Mawrin C, Dreyer E
Brain Res Bull . 2004 Mar; 62(6):485-90. PMID: 15036562
Axonal trauma leads to a series of pathologic events that can culminate in neuronal death. Optic nerve crush can be used to explore histologic and molecular changes in traumatic central...