Christian H Ottensmeier
Overview
Explore the profile of Christian H Ottensmeier including associated specialties, affiliations and a list of published articles.
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101
Citations
10724
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Recent Articles
21.
Wang C, Zainal N, Chai S, Dickie J, Gan C, Zulaziz N, et al.
Front Immunol
. 2021 Nov;
12:763086.
PMID: 34733290
HPV-independent head and neck squamous cell carcinoma (HNSCC) is a common cancer globally. The overall response rate to anti-PD1 checkpoint inhibitors (CPIs) in HNSCC is ~16%. One major factor influencing...
22.
Bulloni M, Sandrini G, Stacchiotti I, Barberis M, Calabrese F, Carvalho L, et al.
Cancers (Basel)
. 2021 Oct;
13(19).
PMID: 34638359
Lung neuroendocrine neoplasms (lung NENs) are categorised by morphology, defining a classification sometimes unable to reflect ultimate clinical outcome. Subjectivity and poor reproducibility characterise diagnosis and prognosis assessment of all...
23.
Eschweiler S, Clarke J, Ramirez-Suastegui C, Panwar B, Madrigal A, Chee S, et al.
Nat Immunol
. 2021 Jun;
22(8):1052-1063.
PMID: 34168370
Immune-checkpoint blockade (ICB) has shown remarkable clinical success in boosting antitumor immunity. However, the breadth of its cellular targets and specific mode of action remain elusive. We find that tumor-infiltrating...
24.
Tanno L, Naheed S, Dunbar J, Tod J, Lopez M, Taylor J, et al.
Neuroendocrinology
. 2021 Jun;
112(4):370-383.
PMID: 34157710
Introduction: Neuroendocrine tumours (NETs) are rare tumours with an increasing incidence. While low- and intermediate-grade pancreatic NET (PanNET) and small intestinal NET (siNET) are slow growing, they have a relatively...
25.
Waise S, Parker R, Rose-Zerilli M, Layfield D, Wood O, West J, et al.
Bio Protoc
. 2021 Mar;
9(23):e3440.
PMID: 33654935
Despite their involvement in many physiological and pathological processes, fibroblasts remain a poorly-characterized cell type. Analysis of primary fibroblasts while maintaining their phenotype is challenging: standard methods for fibroblast isolation...
26.
von Witzleben A, Currall E, Wood O, Chudley L, Akinyegun O, Thomas J, et al.
Front Oncol
. 2021 Feb;
10:591063.
PMID: 33575210
Introduction: Human papillomavirus 16 (HPV16) is the main cause of oropharyngeal squamous cell carcinoma (OPSCC). To date, the links between HPV16 gene expression and adaptive immune responses have not been...
27.
Kusnadi A, Ramirez-Suastegui C, Fajardo V, Chee S, Meckiff B, Simon H, et al.
Sci Immunol
. 2021 Jan;
6(55).
PMID: 33478949
The molecular properties of CD8 T cells that respond to SARS-CoV-2 infection are not fully known. Here, we report on the single-cell transcriptomes of >80,000 virus-reactive CD8 T cells, obtained...
28.
von Witzleben A, Fehn A, Grages A, Ezic J, Jeske S, Puntigam L, et al.
Int J Cancer
. 2020 Dec;
148(8):2023-2035.
PMID: 33336372
Programmed-death-1 (PD1) antibodies are approved for recurrent and metastatic head and neck squamous cell carcinoma. Multiple drugs targeting costimulatory and coinhibitory immune checkpoint molecules (ICM) have been discovered. However, it...
29.
Savelyeva N, Ottensmeier C
Blood
. 2020 Dec;
136(24):2722-2723.
PMID: 33301032
No abstract available.
30.
Schmiedel B, Chandra V, Rocha J, Gonzalez-Colin C, Bhattacharyya S, Madrigal A, et al.
bioRxiv
. 2020 Dec;
PMID: 33299987
Common genetic polymorphisms associated with severity of COVID-19 illness can be utilized for discovering molecular pathways and cell types driving disease pathogenesis. Here, we assessed the effects of 679 COVID-19-risk...