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Christian Eisen

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Articles 14
Citations 711
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Recent Articles
1.
Levy S, Herrler J, Liebert A, Tkotz K, Fabian M, Eisen C, et al.
Magn Reson Med . 2022 Sep; 89(1):77-94. PMID: 36128895
Purpose: To evaluate the benefits and challenges of dynamic parallel transmit (pTx) pulses for fat saturation (FS) and water-excitation (WE), in the context of CEST MRI. Methods: "Universal" k -points...
2.
Berghoff A, Liao Y, Karreman M, Ilhan-Mutlu A, Gunkel K, Sprick M, et al.
Mol Cancer Res . 2021 Jan; 19(4):688-701. PMID: 33443114
Specific biological properties of those circulating cancer cells that are the origin of brain metastases (BM) are not well understood. Here, single circulating breast cancer cells were fate-tracked during all...
3.
Kuhlmann L, Nadler W, Kerner A, Hanke S, Noll E, Eisen C, et al.
Pancreas . 2016 Nov; 46(3):311-322. PMID: 27846146
Objectives: Pancreatic ductal adenocarcinoma (PDAC) has been subclassified into 3 molecular subtypes: classical, quasi-mesenchymal, and exocrine-like. These subtypes exhibit differences in patient survival and drug resistance to conventional therapies. The...
4.
Noll E, Eisen C, Stenzinger A, Espinet E, Muckenhuber A, Klein C, et al.
Nat Med . 2016 Feb; 22(3):278-87. PMID: 26855150
Although subtypes of pancreatic ductal adenocarcinoma (PDAC) have been described, this malignancy is clinically still treated as a single disease. Here we present patient-derived models representing the full spectrum of...
5.
Hofner T, Klein C, Eisen C, Rigo-Watermeier T, Haferkamp A, Sprick M
J Cell Mol Med . 2016 Feb; 20(4):721-30. PMID: 26849468
The long-term propagation of basal prostate progenitor cells ex vivo has been very difficult in the past. The development of novel methods to expand prostate progenitor cells in vitro allows...
6.
Hofner T, Klein C, Eisen C, Rigo-Watermeier T, Haferkamp A, Trumpp A, et al.
Prostate . 2015 Oct; 76(1):114-21. PMID: 26444457
Background: Based on findings of surface marker, protein screens as well as the postulated near-urethral location of the prostate stem cell niche, we were interested whether androgen ablation, distinct anatomic...
7.
Hofner T, Eisen C, Klein C, Rigo-Watermeier T, Goeppinger S, Jauch A, et al.
Stem Cell Reports . 2015 Feb; 4(3):503-18. PMID: 25702639
Methods to isolate and culture primary prostate epithelial stem/progenitor cells (PESCs) have proven difficult and ineffective. Here, we present a method to grow and expand both murine and human basal...
8.
Medyouf H, Mossner M, Jann J, Nolte F, Raffel S, Herrmann C, et al.
Cell Stem Cell . 2014 Apr; 14(6):824-37. PMID: 24704494
Myelodysplastic syndromes (MDSs) are a heterogeneous group of myeloid neoplasms with defects in hematopoietic stem and progenitor cells (HSPCs) and possibly the HSPC niche. Here, we show that patient-derived mesenchymal...
9.
Hofner T, Macher-Goeppinger S, Klein C, Schillert A, Eisen C, Wagner S, et al.
Urol Oncol . 2014 Mar; 32(5):678-86. PMID: 24631171
Objectives: To evaluate CD24/CD44/CD47 cancer stem cell marker expressions in bladder cancer (BCa) and provide data on their prognostic significance for clinical outcome in patients undergoing radical cystectomy (RC). Material...
10.
Hofner T, Zeier M, Hatiboglu G, Eisen C, Schonberg G, Hadaschik B, et al.
World J Urol . 2013 Dec; 32(6):1537-42. PMID: 24370691
Purpose: To evaluate the influence of type 2 diabetes on cancer-specific outcome in patients undergoing surgery for localized renal cell carcinoma (RCC). Methods: A total of 1,140 patients with localized...