Christian D Lorenz
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Explore the profile of Christian D Lorenz including associated specialties, affiliations and a list of published articles.
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88
Citations
504
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Recent Articles
11.
Zhong Z, Ulmschneider M, Lorenz C
ACS Omega
. 2024 Jul;
9(26):28715-28725.
PMID: 38973875
Alzheimer's disease (AD) is a widespread neurodegenerative condition affecting millions globally. Recent research has implicated variants of the triggering receptor expressed in myeloid cells 2 (TREM2) as risk factors for...
12.
Rehman S, Antonovic A, McIntire I, Zheng H, Cleaver L, Baczynska M, et al.
Nat Commun
. 2024 Jun;
15(1):4912.
PMID: 38851738
Bacterial adhesion is a fundamental process which enables colonisation of niche environments and is key for infection. However, in Legionella pneumophila, the causative agent of Legionnaires' disease, these processes are...
13.
Clarke M, Hind C, Ferguson P, Manzo G, Mistry B, Yue B, et al.
NPJ Antimicrob Resist
. 2024 Apr;
1(1):8.
PMID: 38686212
Some antimicrobial peptides (AMPs) have potent bactericidal activity and are being considered as potential alternatives to classical antibiotics. In response to an infection, such AMPs are often produced in animals...
14.
Chiramba C, Moller D, Lorenz C, Chirombo R, Mason A, Bester M, et al.
ACS Omega
. 2024 Apr;
9(13):15556-15572.
PMID: 38585074
WHO has identified several species including as critical priority fungal pathogens due to greater infection prevalence and formation of recalcitrant biofilms. Novel antifungal agents are urgently needed, and antimicrobial peptides...
15.
Lorenz C, Curtis M, Garnett J
Methods Mol Biol
. 2024 Mar;
2778:331-344.
PMID: 38478287
The type 9 secretion system (T9SS) is a recently discovered machinery that both transports cargo proteins across the Gram-negative bacterial outer membrane and attaches them to lipopolysaccharides on the extracellular...
16.
Chalek K, Soni A, Lorenz C, Holland G
Biomacromolecules
. 2024 Feb;
25(3):1916-1922.
PMID: 38315982
Selective one-dimensional C-C spin-diffusion solid-state nuclear magnetic resonance (SSNMR) provides evidence for CH/π ring packing interactions between Pro and Tyr residues in C-enriched dragline silk. The secondary structure of Pro-containing...
17.
Lopez-Rios de Castro R, Ziolek R, Ulmschneider M, Lorenz C
Nano Lett
. 2024 Feb;
24(6):2011-2017.
PMID: 38306708
Polymeric nanoparticles are a highly promising drug delivery formulation. However, a lack of understanding of the molecular mechanisms that underlie their drug solubilization and controlled release capabilities has hindered the...
18.
Xie J, Pink D, Jayne Lawrence M, Lorenz C
Nanoscale
. 2024 Jan;
16(5):2642-2653.
PMID: 38229565
Lipid-based drug carriers are an attractive option to solubilise poorly water soluble therapeutics. Previously, we reported that the digestion of a short tail PC lipid (2C6PC) by the PLA2 enzyme...
19.
Putri A, Hsu M, Han C, Chao F, Hsu C, Lorenz C, et al.
Nanoscale
. 2023 Oct;
15(44):17825-17838.
PMID: 37850423
Albumin nanoparticles (NPs) and PEGylated liposomes have garnered tremendous interest as therapeutic drug carriers due to their unique physicochemical properties. These unique properties also have significant effects on the composition...
20.
Lopez-Rios de Castro R, Ziolek R, Lorenz C
Nanoscale
. 2023 Sep;
15(37):15230-15237.
PMID: 37671739
Contemporary synthetic chemistry approaches can be used to yield a range of distinct polymer topologies with precise control. The topology of a polymer strongly influences its self-assembly into complex nanostructures...