Christian Binsch
Overview
Explore the profile of Christian Binsch including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
60
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Recent Articles
1.
Turewicz M, Skagen C, Hartwig S, Majda S, Thedinga K, Herwig R, et al.
Nat Commun
. 2025 Feb;
16(1):1570.
PMID: 39939313
Insulin is a pleiotropic hormone that elicits its metabolic and mitogenic actions through numerous rapid and reversible protein phosphorylations. The temporal regulation of insulin's intracellular signaling cascade is highly complex...
2.
Zaharia O, Strassburger K, Knebel B, Binsch C, Kupriyanova Y, Moser C, et al.
Diabetes Metab Syndr
. 2024 Oct;
18(10):103137.
PMID: 39427597
Aims: We examined the association of the G allele in the single-nucleotide polymorphism (SNP) rs738409 in the third exon of patatin-like phospholipase domain-containing 3 gene (PNPLA3) gene, with chronic kidney...
3.
Springer C, Binsch C, Weide D, Toska L, Cremer A, Backes H, et al.
Diabetes
. 2024 Apr;
73(7):1058-1071.
PMID: 38608276
Article Highlights:
4.
Altenhofen D, Khuong J, Kuhn T, Lebek S, Gorigk S, Kaiser K, et al.
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36614300
Type 2 diabetes (T2D) represents a multifactorial metabolic disease with a strong genetic predisposition. Despite elaborate efforts in identifying the genetic variants determining individual susceptibility towards T2D, the majority of...
5.
Gorigk S, Ouwens D, Kuhn T, Altenhofen D, Binsch C, Damen M, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2022 Apr;
1867(6):159153.
PMID: 35367353
Changes in intracellular CoA levels are known to contribute to the development of non-alcoholic fatty liver disease (NAFLD) in type 2 diabetes (T2D) in human and rodents. However, the underlying...
6.
Klymenko O, Brecklinghaus T, Dille M, Springer C, de Wendt C, Altenhofen D, et al.
Mol Metab
. 2020 Aug;
42:101062.
PMID: 32771698
Objective: Physical exercise training is associated with increased glucose uptake in skeletal muscle and improved glycemic control. HDAC5, a class IIa histone deacetylase, has been shown to regulate transcription of...
7.
Jelenik T, Dille M, Muller-Luhlhoff S, Kabra D, Zhou Z, Binsch C, et al.
Mol Metab
. 2018 Jul;
16:126-138.
PMID: 29980484
Objective: Post-traumatic stress disorder (PTSD) increases type 2 diabetes risk, yet the underlying mechanisms are unclear. We investigated how early-life exposure to chronic stress affects long-term insulin sensitivity. Methods: C57Bl/6J...
8.
Engelowski E, Schneider A, Franke M, Xu H, Clemen R, Lang A, et al.
Nat Commun
. 2018 May;
9(1):2034.
PMID: 29789554
Cytokine-induced signal transduction is executed by natural biological switches, which among many others control immune-related processes. Here, we show that synthetic cytokine receptors (SyCyRs) can induce cytokine signaling using non-physiological...