Christel Valencia
Overview
Explore the profile of Christel Valencia including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
259
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0
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Recent Articles
1.
Berthome Y, Gerber J, Hanser F, Riche S, Humbert N, Valencia C, et al.
Bioconjug Chem
. 2024 Jul;
35(8):1182-1189.
PMID: 38982626
Fluorogenic dimers with polarity-sensitive folding are powerful probes for live-cell bioimaging. They switch on their fluorescence only after interacting with their targets, thus leading to a high signal-to-noise ratio in...
2.
Maujean T, Wagner P, Valencia C, Riche S, Iturrioz X, Villa P, et al.
Bioconjug Chem
. 2022 Dec;
34(1):162-168.
PMID: 36534753
Herein, we describe a catalyst-free thia-Diels-Alder cycloaddition for the chemoselective labeling of fully deprotected phosphonodithioester-peptides in solution with fluorophores functionalized with an exocyclic diene. The reaction was optimized on the...
3.
Hanser F, Marsol C, Valencia C, Villa P, Klymchenko A, Bonnet D, et al.
ACS Chem Biol
. 2021 Mar;
16(4):651-660.
PMID: 33733725
The local lipid microenvironment of transmembrane receptors is an essential factor in G protein coupled receptor (GPCR) signaling. However, tools are currently missing for studying endogenously expressed GPCRs in primary...
4.
Frantz M, Pellissier L, Pflimlin E, Loison S, Gandia J, Marsol C, et al.
J Med Chem
. 2018 Sep;
61(19):8670-8692.
PMID: 30199637
Oxytocin (OT) and its receptor (OT-R) are implicated in the etiology of autism spectrum disorders (ASD), and OT-R is a potential target for therapeutic intervention. Very few nonpeptide oxytocin agonists...
5.
Valencia C, Dujet C, Margathe J, Iturrioz X, Roux T, Trinquet E, et al.
ChemMedChem
. 2017 Apr;
12(12):925-931.
PMID: 28374567
Analogues of apelin-13 carrying diverse spacers and an ad hoc DY647-derived fluorophore were designed and synthesized by chemoselective acylation of α-hydrazinopeptides. The resulting probes retain very high affinity and efficacy...
6.
Weill N, Valencia C, Gioria S, Villa P, Hibert M, Rognan D
Mol Inform
. 2016 Jul;
30(6-7):521-6.
PMID: 27467153
No abstract available.
7.
Karpenko I, Collot M, Richert L, Valencia C, Villa P, Mely Y, et al.
J Am Chem Soc
. 2014 Dec;
137(1):405-12.
PMID: 25506627
Polarity-sensitive fluorogenic dyes raised considerable attention because they can turn on their fluorescence after binding to biological targets, allowing background-free imaging. However, their brightness is limited, and they do not...
8.
Karpenko I, Kreder R, Valencia C, Villa P, Mendre C, Mouillac B, et al.
Chembiochem
. 2014 Jan;
15(3):359-63.
PMID: 24449564
Classical fluorescence-based approaches to monitor ligand-protein interactions are generally hampered by the background signal of unbound ligand, which must be removed by tedious washing steps. To overcome this major limitation,...
9.
Sulzenbacher G, Roig-Zamboni V, Pagot F, Grisel S, Salomoni A, Valencia C, et al.
Acta Crystallogr D Biol Crystallogr
. 2004 Sep;
60(Pt 10):1855-62.
PMID: 15388933
As part of a structural genomics project on bacterial gene products of unknown function, the crystal structures of YhdH, a putative quinone oxidoreductase, and its complex with NADP have been...
10.
Vincentelli R, Canaan S, Campanacci V, Valencia C, Maurin D, Frassinetti F, et al.
Protein Sci
. 2004 Sep;
13(10):2782-92.
PMID: 15388864
One of the main stumbling blocks encountered when attempting to express foreign proteins in Escherichia coli is the occurrence of amorphous aggregates of misfolded proteins, called inclusion bodies (IB). Developing...