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Valerie Campanacci

Explore the profile of Valerie Campanacci including associated specialties, affiliations and a list of published articles. Areas
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Articles 72
Citations 2522
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Recent Articles
1.
Ammar Khodja L, Campanacci V, Lippens G, Gigant B
PNAS Nexus . 2024 Nov; 3(11):pgae487. PMID: 39534653
Tau is a protein involved in the regulation of axonal microtubules in neurons. In pathological conditions, it forms filamentous aggregates which are molecular markers of neurodegenerative diseases known as tauopathies....
2.
Campanacci V, Gigant B
Biochem Biophys Res Commun . 2023 Oct; 682:244-249. PMID: 37826947
Microtubule dynamics is modulated by many cellular factors including stathmin family proteins. Vertebrate stathmins sequester two αβ-tubulin heterodimers into a tight complex that cannot be incorporated in microtubules. Stathmins are...
3.
Campanacci V, Urvoas A, Ammar Khodja L, Aumont-Nicaise M, Noiray M, Lachkar S, et al.
Proc Natl Acad Sci U S A . 2022 May; 119(19):e2120098119. PMID: 35507869
Microtubule dynamics is regulated by various cellular proteins and perturbed by small-molecule compounds. To what extent the mechanism of the former resembles that of the latter is an open question....
4.
Seul A, Brasiles S, Petitpas I, Lurz R, Campanacci V, Cambillau C, et al.
J Mol Biol . 2021 Jun; 433(18):167112. PMID: 34153288
Siphoviruses are main killers of bacteria. They use a long non-contractile tail to recognize the host cell and to deliver the genome from the viral capsid to the bacterial cytoplasm....
5.
Simanov G, Dang I, Fokin A, Oguievetskaia K, Campanacci V, Cherfils J, et al.
Int J Mol Sci . 2021 Apr; 22(8). PMID: 33923443
During cell migration, protrusion of the leading edge is driven by the polymerization of Arp2/3-dependent branched actin networks. Migration persistence is negatively regulated by the Arp2/3 inhibitory protein Arpin. To...
6.
Knossow M, Campanacci V, Ammar Khodja L, Gigant B
iScience . 2020 Sep; 23(9):101511. PMID: 32920486
Microtubules are cytoskeletal components involved in pivotal eukaryotic functions such as cell division, ciliogenesis, and intracellular trafficking. They assemble from αβ-tubulin heterodimers and disassemble in a process called dynamic instability,...
7.
Vilela F, Velours C, Chenon M, Aumont-Nicaise M, Campanacci V, Thureau A, et al.
Sci Rep . 2019 Nov; 9(1):16036. PMID: 31690808
JIP3 and JIP4 (JNK-interacting proteins 3 and 4) are adaptors for cargo recruitment by dynein/dynactin and kinesin1 motors. Both are dimers that are stabilised by two sections of leucine zipper...
8.
Campanacci V, Urvoas A, Cantos-Fernandes S, Aumont-Nicaise M, Arteni A, Velours C, et al.
Proc Natl Acad Sci U S A . 2019 May; 116(20):9859-9864. PMID: 31036638
Nucleation is one of the least understood steps of microtubule dynamics. It is a kinetically unfavorable process that is templated in the cell by the γ-tubulin ring complex or by...
9.
Campanacci V, Urvoas A, Consolati T, Cantos-Fernandes S, Aumont-Nicaise M, Valerio-Lepiniec M, et al.
Structure . 2019 Jan; 27(3):497-506.e4. PMID: 30661854
Microtubules are cytoskeletal filaments of eukaryotic cells made of αβ-tubulin heterodimers. Structural studies of non-microtubular tubulin rely mainly on molecules that prevent its self-assembly and are used as crystallization chaperones....
10.
Fetics S, Thureau A, Campanacci V, Aumont-Nicaise M, Dang I, Gautreau A, et al.
Structure . 2016 Jan; 24(2):252-60. PMID: 26774128
Arpin is a newly discovered regulator of actin polymerization at the cell leading edge, which steers cell migration by exerting a negative control on the Arp2/3 complex. Arpin proteins have...