Chris Stubben
Overview
Explore the profile of Chris Stubben including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
734
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0
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Recent Articles
1.
Allen-Brady K, Clayton F, Hazel M, Stevens J, Pyne A, Pletneva M, et al.
Gastroenterology
. 2025 Feb;
PMID: 39914776
Background & Aims: Evidence for a genetic contribution to eosinophilic esophagitis (EoE) exists from family and genome-wide association studies. Extensive investigation into rare variants contributing to EoE has not been...
2.
Deacon D, Stubben C, Marcacci E, Stone C, Birdsall M, Florell S, et al.
J Invest Dermatol
. 2024 Aug;
145(3):707-709.e2.
PMID: 39182561
No abstract available.
3.
Wee Y, Wang J, Wilson E, Rich C, Rogers A, Tong Z, et al.
Nat Commun
. 2024 Aug;
15(1):6613.
PMID: 39098861
Tumour-host immune interactions lead to complex changes in the tumour microenvironment (TME), impacting progression, metastasis and response to therapy. While it is clear that cancer cells can have the capacity...
4.
Wee Y, Wang J, Wilson E, Rich C, Rogers A, Tong Z, et al.
bioRxiv
. 2023 Oct;
PMID: 37873189
Adaptive immune resistance (AIR) is a protective process used by cancer to escape elimination by CD8 T cells. Inhibition of immune checkpoints PD-1 and CTLA-4 specifically target Interferon-gamma (IFNγ)-driven AIR....
5.
Ghazaryan A, Wallace J, Tang W, Barba C, Lee S, Bauer K, et al.
Front Genet
. 2023 May;
14:1192799.
PMID: 37229187
Acute myeloid leukemia (AML) is a heterogeneous and deadly disease characterized by uncontrolled expansion of malignant blasts. Altered metabolism and dysregulated microRNA (miRNA) expression profiles are both characteristic of AML....
6.
Zhang T, Alonzo I, Stubben C, Geng Y, Herdman C, Chandler N, et al.
Dis Model Mech
. 2023 May;
16(7).
PMID: 37183607
Sphingolipidoses are a subcategory of lysosomal storage diseases (LSDs) caused by mutations in enzymes of the sphingolipid catabolic pathway. Like many LSDs, neurological involvement in sphingolipidoses leads to early mortality...
7.
Campbell R, Manne B, Banerjee M, Middleton E, Ajanel A, Schwertz H, et al.
J Clin Invest
. 2022 Oct;
132(23).
PMID: 36194487
Platelets and megakaryocytes are critical players in immune responses. Recent reports suggest infection and inflammation alter the megakaryocyte and platelet transcriptome to induce altered platelet reactivity. We determined whether nonviral...
8.
Orstad G, Fort G, Parnell T, Jones A, Stubben C, Lohman B, et al.
Dev Cell
. 2022 Jul;
57(15):1866-1882.e10.
PMID: 35835117
Changes in cellular identity (also known as histologic transformation or lineage plasticity) can drive malignant progression and resistance to therapy in many cancers, including lung adenocarcinoma (LUAD). The lineage-specifying transcription...
9.
Camolotto S, Belova V, Torre-Healy L, Vahrenkamp J, Berrett K, Conway H, et al.
Gut
. 2020 Aug;
70(5):900-914.
PMID: 32826305
Objective: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a 5-year survival of less than 5%. Transcriptomic analysis has identified two clinically relevant molecular subtypes of PDAC: classical and...
10.
Manne B, Denorme F, Middleton E, Portier I, Rowley J, Stubben C, et al.
Blood
. 2020 Jun;
136(11):1317-1329.
PMID: 32573711
There is an urgent need to understand the pathogenesis of coronavirus disease 2019 (COVID-19). In particular, thrombotic complications in patients with COVID-19 are common and contribute to organ failure and...