» Authors » Chris Molenaar

Chris Molenaar

Explore the profile of Chris Molenaar including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 22
Citations 610
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Kapustin A, Tsakali S, Whitehead M, Chennell G, Wu M, Molenaar C, et al.
bioRxiv . 2023 Aug; PMID: 37645762
The extracellular matrix (ECM) supports blood vessel architecture and functionality and undergoes active remodelling during vascular repair and atherogenesis. Vascular smooth muscle cells (VSMCs) are essential for vessel repair and,...
2.
Silao F, Ryman K, Jiang T, Ward M, Hansmann N, Molenaar C, et al.
PLoS Pathog . 2021 Aug; 17(8):e1009877. PMID: 34460867
[This corrects the article DOI: 10.1371/journal.ppat.1008328.].
3.
Beretta M, Santos C, Molenaar C, Hafstad A, Miller C, Revazian A, et al.
EMBO J . 2020 Oct; 39(19):e103530. PMID: 33001475
Cells subjected to environmental stresses undergo regulated cell death (RCD) when homeostatic programs fail to maintain viability. A major mechanism of RCD is the excessive calcium loading of mitochondria and...
4.
Silao F, Ryman K, Jiang T, Ward M, Hansmann N, Molenaar C, et al.
PLoS Pathog . 2020 Sep; 16(9):e1008328. PMID: 32936835
Candida albicans cells depend on the energy derived from amino acid catabolism to induce and sustain hyphal growth inside phagosomes of engulfing macrophages. The concomitant deamination of amino acids is...
5.
Porter L, Minaisah R, Ahmed S, Ali S, Norton R, Zhang Q, et al.
Cells . 2020 Jan; 9(1). PMID: 31935926
Vascular smooth muscle cells (VSMCs) are the predominant cell type in the blood vessel wall. Changes in VSMC actomyosin activity and morphology are prevalent in cardiovascular disease. The actin cytoskeleton...
6.
Molenaar C, Weeks K
Clin Exp Pharmacol Physiol . 2018 May; 45(10):1087-1094. PMID: 29772060
Nucleocytoplasmic protein shuttling is integral to the transmission of signals between the nucleus and the cytoplasm. The nuclear/cytoplasmic distribution of proteins of interest can be determined via fluorescence microscopy, following...
7.
Misaka T, Murakawa T, Nishida K, Omori Y, Taneike M, Omiya S, et al.
J Mol Cell Cardiol . 2017 Nov; 114:93-104. PMID: 29129702
Protein quality control in cardiomyocytes is crucial to maintain cellular homeostasis. The accumulation of damaged organelles, such as mitochondria and misfolded proteins in the heart is associated with heart failure....
8.
Suna G, Wojakowski W, Lynch M, Barallobre-Barreiro J, Yin X, Mayr U, et al.
Circulation . 2017 Oct; 137(2):166-183. PMID: 29030347
Background: Extracellular matrix (ECM) remodeling contributes to in-stent restenosis and thrombosis. Despite its important clinical implications, little is known about ECM changes post-stent implantation. Methods: Bare-metal and drug-eluting stents were...
9.
Weeks K, Ranieri A, Karas A, Bernardo B, Ashcroft A, Molenaar C, et al.
J Am Heart Assoc . 2017 Mar; 6(4). PMID: 28343149
Background: Class IIa histone deacetylase (HDAC) isoforms such as HDAC5 are critical signal-responsive repressors of maladaptive cardiomyocyte hypertrophy, through nuclear interactions with transcription factors including myocyte enhancer factor-2. β-Adrenoceptor (β-AR)...
10.
Langley S, Willeit K, Didangelos A, Matic L, Skroblin P, Barallobre-Barreiro J, et al.
J Clin Invest . 2017 Mar; 127(4):1546-1560. PMID: 28319050
Background: The identification of patients with high-risk atherosclerotic plaques prior to the manifestation of clinical events remains challenging. Recent findings question histology- and imaging-based definitions of the "vulnerable plaque," necessitating...