Chris Molenaar
Overview
Explore the profile of Chris Molenaar including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
610
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0
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Recent Articles
11.
Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling
Santos C, Hafstad A, Beretta M, Zhang M, Molenaar C, Kopec J, et al.
EMBO J
. 2016 Jan;
35(3):319-34.
PMID: 26742780
Phosphorylation of translation initiation factor 2α (eIF2α) attenuates global protein synthesis but enhances translation of activating transcription factor 4 (ATF4) and is a crucial evolutionarily conserved adaptive pathway during cellular...
12.
Rzeniewicz K, Newe A, Rey Gallardo A, Davies J, Holt M, Patel A, et al.
Proc Natl Acad Sci U S A
. 2015 Mar;
112(12):E1461-70.
PMID: 25775539
L-selectin is a cell adhesion molecule that tethers free-flowing leukocytes from the blood to luminal vessel walls, facilitating the initial stages of their emigration from the circulation toward an extravascular...
13.
Zampetaki A, Attia R, Mayr U, Gomes R, Phinikaridou A, Yin X, et al.
Circ Res
. 2014 Sep;
115(10):857-66.
PMID: 25201911
Rationale: Abdominal aortic aneurysms constitute a degenerative process in the aortic wall. Both the miR-29 and miR-15 families have been implicated in regulating the vascular extracellular matrix. Objective: Our aim...
14.
Krouwels I, Wiesmeijer K, Abraham T, Molenaar C, Verwoerd N, Tanke H, et al.
J Cell Biol
. 2005 Aug;
170(4):537-49.
PMID: 16103223
Trimethylation of histone H3 lysine 9 and the subsequent binding of heterochromatin protein 1 (HP1) mediate the formation and maintenance of pericentromeric heterochromatin. Trimethylation of H3K9 is governed by the...
15.
Molenaar C, Abdulle A, Gena A, Tanke H, Dirks R
J Cell Biol
. 2004 May;
165(2):191-202.
PMID: 15117966
Many of the protein factors that play a role in nuclear export of mRNAs have been identified, but still little is known about how mRNAs are transported through the cell...
16.
Kalayda G, Jansen B, Molenaar C, Wielaard P, Tanke H, Reedijk J
J Biol Inorg Chem
. 2004 Apr;
9(4):414-22.
PMID: 15071768
The cellular processing of three fluorescent N, N'-bis(aminoalkyl)-1,4-diaminoanthraquinones (aminoalkyl=2-aminoethyl, 3-aminoprop-1-yl or 4-aminobut-1-yl) and their dinuclear platinum complexes in A2780 human ovarian carcinoma cells with acquired resistance to cisplatin has been...
17.
Jansen B, Wielaard P, Kalayda G, Ferrari M, Molenaar C, Tanke H, et al.
J Biol Inorg Chem
. 2004 Apr;
9(4):403-13.
PMID: 15071767
A series of N, N'-bis(aminoalkyl)-1,4-diaminoanthraquinones (aminoalkyl=2-aminoethyl, 3-aminoprop-1-yl and 4-aminobut-1-yl) was functionalized with trans-platinum DNA-binding moieties. Cytotoxicity testing in A2780 human ovarian carcinoma cells revealed high anticancer activity of the formed...
18.
Molenaar C, Wiesmeijer K, Verwoerd N, Khazen S, Eils R, Tanke H, et al.
EMBO J
. 2003 Dec;
22(24):6631-41.
PMID: 14657034
Chromosome ends are protected from degradation by the presence of the highly repetitive hexanucleotide sequence of TTAGGG and associated proteins. These so-called telomeric complexes are suggested to play an important...
19.
Zhang Y, Leliveld S, Kooistra K, Molenaar C, Rohn J, Tanke H, et al.
Exp Cell Res
. 2003 Aug;
289(1):36-46.
PMID: 12941602
Apoptin, a protein derived from chicken anemia virus, induces apoptosis in human transformed or tumor cells but not in normal cells. When produced in bacteria as a recombinant fusion with...
20.
van Hemert M, Deelder A, Molenaar C, Steensma H, van Heusden G
J Biol Chem
. 2003 Jan;
278(17):15049-55.
PMID: 12551942
The Fin1 protein of the yeast Saccharomyces cerevisiae forms filaments between the spindle pole bodies of dividing cells. In the two-hybrid system it binds to 14-3-3 proteins, which are highly...