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Chris Gardiner

Explore the profile of Chris Gardiner including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Gardiner C, Echenagucia M, Gosselin R
Semin Thromb Hemost . 2023 Jan; 49(6):634-640. PMID: 36603812
Laboratory-developed tests (LDTs) are widely used in clinical hemostasis laboratories. The extent to which LDTs are regulated varies greatly around the world, and proposed changes to regulations have raised concerns...
2.
Gardiner C, Mackie I, MacCallum P, Platton S
Int J Lab Hematol . 2022 Apr; 44(5):817-822. PMID: 35451557
Background: Severe coronavirus disease 2019 (COVID-19) is characterized by marked hypoxaemia and lung oedema, often accompanied by disordered blood coagulation and fibrinolytic systems, endothelial damage and intravascular fibrin deposition. Patients/methods:...
3.
Gardiner C, Lane P, Tailor H, Machin S, Mackie I
Int J Lab Hematol . 2021 Jul; 43(6):1593-1598. PMID: 34252265
Background: The Sysmex CN-6500 is a new haemostasis analyser with an integrated immunoassay module that performs chemiluminescence enzyme assay (CLEIA) in addition to coagulation, turbidimetric, chromogenic and platelet aggregation tests....
4.
Price J, Gardiner C, Harrison P
Transfusion . 2021 May; 61(7):2179-2194. PMID: 33948950
Background: Platelet transfusion is challenging in emergency medicine because of short platelet shelf life and stringent storage conditions. Platelet-derived extracellular vesicles (PEV) exhibit platelet-like properties. A plasma generated from expired...
5.
Gardiner C, Coleman R, de Maat M, Dorgalaleh A, Echenagucia M, Gosselin R, et al.
Int J Lab Hematol . 2021 Apr; 43(5):907-916. PMID: 33876567
Before a new method is used for clinical testing, it is essential that it is evaluated for suitability for its intended purpose. This document gives guidance for the performance, verification...
6.
Gardiner C, Coleman R, de Maat M, Dorgalaleh A, Echenagucia M, Gosselin R, et al.
Int J Lab Hematol . 2020 Nov; 43(2):169-183. PMID: 33249720
Before a new method is used for clinical testing, it is essential that it is evaluated for suitability for its intended purpose. This document gives guidance for the performance of...
7.
Gardiner C, Lane P, Langley K, Tailor H, Machin S, Mackie I
Int J Lab Hematol . 2020 Sep; 42(5):643-649. PMID: 32885901
Background: The CN-6000 (Sysmex Corp.) is a new haemostasis analyser with blood coagulation, amidolytic, immuno-turbidometric and light transmission aggregometry (LTA) capabilities. Transmitted light is monitored at multiple wavelengths (340, 405,...
8.
Gardiner C, Lane P, Tailor H, Mackie I
Int J Lab Hematol . 2019 Nov; 42(2):140-144. PMID: 31769186
Introduction: Plasma samples with gross lipaemia present a challenge for coagulation laboratories using optical analysers. High-speed centrifugation may be used to remove excess lipids but it has not established whether...
9.
Bradbury C, Fletcher K, Sun Y, Heneghan C, Gardiner C, Roalfe A, et al.
Br J Haematol . 2019 Nov; 188(6):962-975. PMID: 31713863
Venous thromboembolism (VTE) is prevalent and impactful, with a risk of death, morbidity and recurrence. Post-thrombotic syndrome (PTS) is a common consequence and associated with impaired quality of life (QoL)....
10.
Izco M, Blesa J, Schleef M, Schmeer M, Porcari R, Al-Shawi R, et al.
Mol Ther . 2019 Sep; 27(12):2111-2122. PMID: 31501034
The development of new therapies to slow down or halt the progression of Parkinson's disease is a health care priority. A key pathological feature is the presence of alpha-synuclein aggregates,...