Aled Clayton
Overview
Explore the profile of Aled Clayton including associated specialties, affiliations and a list of published articles.
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72
Citations
14407
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Recent Articles
1.
Zhang X, Dumcius P, Mikhaylov R, Qi J, Stringer M, Sun C, et al.
Adv Sci (Weinh)
. 2024 Aug;
11(39):e2403574.
PMID: 39136049
Cytopathology, crucial in disease diagnosis, commonly uses microscopic slides to scrutinize cellular abnormalities. However, processing high volumes of samples often results in numerous negative diagnoses, consuming significant time and resources...
2.
Bordanaba-Florit G, Royo F, Alboniga O, Clayton A, Falcon-Perez J, Webber J
Biochim Biophys Acta Mol Basis Dis
. 2024 May;
1870(6):167229.
PMID: 38734319
The prostate gland is a complex and heterogeneous organ composed of epithelium and stroma. Whilst many studies into prostate cancer focus on epithelium, the stroma is known to play a...
3.
Kapustin A, Tsakali S, Whitehead M, Chennell G, Wu M, Molenaar C, et al.
bioRxiv
. 2023 Aug;
PMID: 37645762
The extracellular matrix (ECM) supports blood vessel architecture and functionality and undergoes active remodelling during vascular repair and atherogenesis. Vascular smooth muscle cells (VSMCs) are essential for vessel repair and,...
4.
Hyland M, Mennan C, Davies R, Wilson E, Tonge D, Clayton A, et al.
Stem Cell Rev Rep
. 2023 Jul;
19(7):2391-2406.
PMID: 37474869
Autoimmune conditions, such as rheumatoid arthritis, are characterised by a loss of immune tolerance, whereby the immune cells attack self-antigens causing pain and inflammation. These conditions can be brought into...
5.
Dumcius P, Mikhaylov R, Zhang X, Bareford M, Stringer M, Errington R, et al.
Small
. 2023 Apr;
19(35):e2300390.
PMID: 37118859
Extracellular vesicles (EVs) are secreted nanostructures that play various roles in critical cancer processes. They operate as an intercellular communication system, transferring complex sets of biomolecules from cell to cell....
6.
Wang H, Boardman J, Zhang X, Sun C, Cai M, Wei J, et al.
Anal Chim Acta
. 2023 Apr;
1255:341120.
PMID: 37032048
Acoustofluidic devices becomes one of the emerging and versatile tools for many biomedical applications. Most of the previous acoustofluidic devices are used for cells manipulation, and the few devices for...
7.
Owen J, Clayton A, Pearson H
Biomolecules
. 2023 Jan;
13(1).
PMID: 36671452
The continuous remodeling of the tumor microenvironment (TME) during prostate tumorigenesis is emerging as a critical event that facilitates cancer growth, progression and drug-resistance. Recent advances have identified extensive communication...
8.
Knight R, Board-Davies E, Brown H, Clayton A, Davis T, Karatas B, et al.
Stem Cells Transl Med
. 2022 Jun;
11(8):861-875.
PMID: 35716044
Scar formation during wound repair can be devastating for affected individuals. Our group previously documented the therapeutic potential of novel progenitor cell populations from the non-scarring buccal mucosa. These Oral...
9.
van Niel G, Carter D, Clayton A, Lambert D, Raposo G, Vader P
Nat Rev Mol Cell Biol
. 2022 Mar;
23(5):369-382.
PMID: 35260831
Extracellular vesicles (EVs) are increasingly recognized as important mediators of intercellular communication. They have important roles in numerous physiological and pathological processes, and show considerable promise as novel biomarkers of...
10.
Shephard A, Giles P, Mbengue M, Alraies A, Spary L, Kynaston H, et al.
J Extracell Vesicles
. 2021 Oct;
10(12):e12150.
PMID: 34596356
Histological assessment of prostate cancer is the key diagnostic test and can predict disease outcome. This is however an invasive procedure that carries associated risks, hence non-invasive assays to support...