Chris D Vulpe
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Explore the profile of Chris D Vulpe including associated specialties, affiliations and a list of published articles.
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67
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1653
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Recent Articles
1.
Kim J, Ofori S, Tagmount A, Vulpe C, Awuah S
ACS Omega
. 2022 Nov;
7(43):39197-39205.
PMID: 36340096
Metal-based drugs, such as cisplatin and auranofin, are used for the treatment of cancer and rheumatoid arthritis, respectively. Auranofin and other gold-derived compounds have been shown to possess anticancer, anti-inflammatory,...
2.
Pallares R, An D, Hebert S, Loguinov A, Proctor M, Villalobos J, et al.
ACS Omega
. 2022 Oct;
7(38):34412-34419.
PMID: 36188298
Lanthanides are a series of elements essential to a wide range of applications, from clean energy production to healthcare. Despite their presence in multiple products and technologies, their toxicological characteristics...
3.
Grodzki M, Bluhm A, Schaefer M, Tagmount A, Russo M, Sobh A, et al.
Genome Med
. 2022 Jan;
14(1):10.
PMID: 35086559
Background: The COVID-19 pandemic has resulted in 275 million infections and 5.4 million deaths as of December 2021. While effective vaccines are being administered globally, there is still a great...
4.
Russo M, Humes S, Figueroa A, Tagmount A, Zhang P, Loguinov A, et al.
Toxicol Sci
. 2021 May;
182(2):260-274.
PMID: 34051100
Organochlorine pesticides (OCPs) are persistent pollutants linked to diverse adverse health outcomes. Environmental exposure to OCPs has been suggested to negatively impact the immune system but their effects on cellular...
5.
Zhao Y, Wei L, Tagmount A, Loguinov A, Sobh A, Hubbard A, et al.
Chemosphere
. 2020 Nov;
269:128701.
PMID: 33189395
Formaldehyde (FA), a ubiquitous environmental pollutant, is classified as a Group I human carcinogen by the International Agency for Research on Cancer. Previously, we reported that FA induced hematotoxicity and...
6.
Russo M, Sobh A, Zhang P, Loguinov A, Tagmount A, Vulpe C, et al.
Toxicol Sci
. 2020 May;
176(2):366-381.
PMID: 32421776
Organochlorine pesticides, once widely used, are extremely persistent and bio-accumulative in the environment. Epidemiological studies have implicated that environmental exposure to organochlorine pesticides including dieldrin is a risk factor for...
7.
Thingholm L, Ruhlemann M, Koch M, Fuqua B, Laucke G, Boehm R, et al.
Cell Host Microbe
. 2019 Aug;
26(2):252-264.e10.
PMID: 31399369
Obesity and type 2 diabetes (T2D) are metabolic disorders that are linked to microbiome alterations. However, their co-occurrence poses challenges in disentangling microbial features unique to each condition. We analyzed...
8.
Sobh A, Loguinov A, Stornetta A, Balbo S, Tagmount A, Zhang L, et al.
Toxicol Sci
. 2019 May;
169(1):235-245.
PMID: 31059574
Acetaldehyde, a metabolite of ethanol, is a cellular toxicant and a human carcinogen. A genome-wide CRISPR-based loss-of-function screen in erythroleukemic K562 cells revealed candidate genetic contributors affecting acetaldehyde cytotoxicity. Secondary...
9.
Sobh A, Loguinov A, Yazici G, Zeidan R, Tagmount A, Hejazi N, et al.
Toxicol Sci
. 2019 Mar;
169(1):108-121.
PMID: 30815697
Arsenic exposure is a worldwide health concern associated with an increased risk of skin, lung, and bladder cancer but arsenic trioxide (AsIII) is also an effective chemotherapeutic agent. The current...
10.
Ma F, Fuqua B, Hasin Y, Yukhtman C, Vulpe C, Lusis A, et al.
BMC Genomics
. 2019 Jan;
20(1):9.
PMID: 30616562
Background: 3' RNA sequencing provides an alternative to whole transcript analysis. However, we do not know a priori the relative advantage of each method. Thus, a comprehensive comparison between the...