Chris D Vulpe
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Explore the profile of Chris D Vulpe including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Fuqua B, Lu Y, Frazer D, Darshan D, Wilkins S, Dunn L, et al.
Cell Mol Gastroenterol Hepatol
. 2018 Sep;
6(4):405-427.
PMID: 30182051
Background & Aims: Multicopper ferroxidases (MCFs) facilitate intestinal iron absorption and systemic iron recycling, likely by a mechanism involving the oxidization of Fe from the iron exporter ferroportin 1 for...
12.
Blalock B, Robinson W, Loguinov A, Vulpe C, Krick K, Poynton H
Environ Sci Technol
. 2018 Jun;
52(16):9419-9430.
PMID: 29953215
Transcriptomics, high-throughput assays, and adverse outcome pathways (AOP) are promising approaches applied to toxicity monitoring in the 21st century, but development of these methods is challenging for nonmodel organisms and...
13.
Chen M, Zheng J, Liu G, Xu E, Wang J, Fuqua B, et al.
Redox Biol
. 2018 Jun;
17:432-439.
PMID: 29883959
Little is known about the iron efflux from the pancreas, but it is likely that multicopper ferroxidases (MCFs) are involved in this process. We thus used hephaestin (Heph) and ceruloplasmin...
14.
Zheng J, Jiang R, Chen M, Maimaitiming Z, Wang J, Anderson G, et al.
J Nutr
. 2018 Apr;
148(4):643-649.
PMID: 29659961
Background: The accumulation of iron occurs in the central nervous system (CNS) in several neurodegenerative diseases. Although multi-copper ferroxidases (MCFs) play an important role in cellular iron metabolism and homeostasis,...
15.
Poynton H, Hasenbein S, Benoit J, Sepulveda M, Poelchau M, Hughes D, et al.
Environ Sci Technol
. 2018 Apr;
52(10):6009-6022.
PMID: 29634279
Hyalella azteca is a cryptic species complex of epibenthic amphipods of interest to ecotoxicology and evolutionary biology. It is the primary crustacean used in North America for sediment toxicity testing...
16.
Doguer C, Ha J, Gulec S, Vulpe C, Anderson G, Collins J
Blood Adv
. 2018 Jan;
1(17):1335-1346.
PMID: 29296776
Regulation of intestinal iron absorption is crucial to maintain body iron levels because humans have no regulated iron-excretory system. Elucidating molecular events that mediate intestinal iron transport is thus important...
17.
De La Rosa V, Asfaha J, Fasullo M, Loguinov A, Li P, Moore L, et al.
Toxicol Sci
. 2017 Oct;
160(1):111-120.
PMID: 28973557
Trichloroethylene (TCE), an industrial chemical and environmental contaminant, is a human carcinogen. Reactive metabolites are implicated in renal carcinogenesis associated with TCE exposure, yet the toxicity mechanisms of these metabolites...
18.
McLachlan S, Page K, Lee S, Loguinov A, Valore E, Hui S, et al.
Am J Physiol Gastrointest Liver Physiol
. 2017 Aug;
313(5):G511-G523.
PMID: 28798083
Iron homeostasis is tightly regulated, and the peptide hormone hepcidin is considered to be a principal regulator of iron metabolism. Previous studies in a limited number of mouse strains found...
19.
Jiang B, Liu G, Zheng J, Chen M, Maimaitiming Z, Chen M, et al.
Sci Rep
. 2016 Dec;
6:39470.
PMID: 27991585
Multicopper ferroxidases (MCFs) play an important role in cellular iron homeostasis. However, the role of MCFs in renal metabolism remains unclear. We used Hephaestin (Heph) and Ceruloplasmin (Cp) single or...
20.
Functional Toxicogenomic Profiling Expands Insight into Modulators of Formaldehyde Toxicity in Yeast
North M, Gaytan B, Romero Jr C, De La Rosa V, Loguinov A, Smith M, et al.
Front Genet
. 2016 Dec;
7:200.
PMID: 27909446
Formaldehyde (FA) is a commercially important chemical with numerous and diverse uses. Accordingly, occupational and environmental exposure to FA is prevalent worldwide. Various adverse effects, including nasopharyngeal, sinonasal, and lymphohematopoietic...