Chris Chatzinakos
Overview
Explore the profile of Chris Chatzinakos including associated specialties, affiliations and a list of published articles.
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28
Citations
233
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Recent Articles
1.
Barr P, Neale Z, Chatzinakos C, Schulman J, Mullins N, Zhang J, et al.
Complex Psychiatry
. 2025 Mar;
11(1):1-11.
PMID: 40061584
Introduction: Research has identified multiple risk factors associated with suicide attempt (SA) among individuals with psychiatric illness. However, there is limited research among those with an alcohol use disorder (AUD),...
2.
Singh M, Chatzinakos C, Barr P, Gentry A, Bigdeli T, Webb B, et al.
medRxiv
. 2025 Mar;
PMID: 40061314
Most genome-wide association studies (GWASs) of depression focus on broad, heterogeneous outcomes, limiting the discovery of genomic risk loci specific to major depressive disorder (MDD). Previous UK Biobank (UKB) studies...
3.
Davis S, Liu A, Teerlink C, Lapato D, Gorman B, Genovese G, et al.
medRxiv
. 2025 Feb;
PMID: 39974076
Sex chromosome trisomies (SCT) are the most common whole chromosome aneuploidy in humans. Yet, our understanding of the prevalence and associated health outcomes is largely driven by observational studies of...
4.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature
. 2025 Jan;
PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
5.
Barr P, Neale Z, Bigdeli T, Chatzinakos C, Harvey P, Peterson R, et al.
medRxiv
. 2024 Dec;
PMID: 39711727
Importance: Persons with substance use disorders (SUD) often suffer from additional comorbidities, including psychiatric conditions and physical health problems. Researchers have explored this overlap in electronic health records (EHR) using...
6.
Poore H, Chatzinakos C, Mallard T, Sanchez-Roige S, Aliev F, Hatoum A, et al.
medRxiv
. 2024 Dec;
PMID: 39649581
Importance: Substance use disorders (SUDs) frequently co-occur with each other and with other traits related to behavioral disinhibition, a spectrum of outcomes referred to as externalizing. Nevertheless, genome-wide association studies...
7.
Bigdeli T, Chatzinakos C, Bendl J, Barr P, Venkatesh S, Gorman B, et al.
medRxiv
. 2024 Sep;
PMID: 39252912
Large-scale genome-wide association studies of schizophrenia have uncovered hundreds of associated loci but with extremely limited representation of African diaspora populations. We surveyed electronic health records of 200,000 individuals of...
8.
Frohlich A, Gerstner N, Gagliardi M, Kodel M, Yusupov N, Matosin N, et al.
Nat Neurosci
. 2024 Sep;
27(10):2021-2032.
PMID: 39227716
Aging is a complex biological process and represents the largest risk factor for neurodegenerative disorders. The risk for neurodegenerative disorders is also increased in individuals with psychiatric disorders. Here, we...
9.
Daskalakis N, Iatrou A, Chatzinakos C, Jajoo A, Snijders C, Wylie D, et al.
Science
. 2024 May;
384(6698):eadh3707.
PMID: 38781393
The molecular pathology of stress-related disorders remains elusive. Our brain multiregion, multiomic study of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) included the central nucleus of the amygdala,...
10.
Nievergelt C, Maihofer A, Atkinson E, Chen C, Choi K, Coleman J, et al.
Nat Genet
. 2024 Apr;
56(5):792-808.
PMID: 38637617
Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has thus been limited. We performed...