Howard J Edenberg
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Explore the profile of Howard J Edenberg including associated specialties, affiliations and a list of published articles.
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366
Citations
15478
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Recent Articles
1.
Barr P, Neale Z, Chatzinakos C, Schulman J, Mullins N, Zhang J, et al.
Complex Psychiatry
. 2025 Mar;
11(1):1-11.
PMID: 40061584
Introduction: Research has identified multiple risk factors associated with suicide attempt (SA) among individuals with psychiatric illness. However, there is limited research among those with an alcohol use disorder (AUD),...
2.
Johnson E, Lai D, Miller A, Hatoum A, Deak J, Balbona J, et al.
medRxiv
. 2025 Feb;
PMID: 39974067
Genetic research on nicotine dependence has utilized multiple assessments that are in weak agreement. We conducted a genome-wide association study of nicotine dependence defined using the Diagnostic and Statistical Manual...
3.
Hill S, Edenberg H, Corvin A, Thorgeirsson T, Below J, Goldman D, et al.
Genes Brain Behav
. 2025 Feb;
24(1):e70017.
PMID: 39935334
The National Institute of Drug Abuse convened a panel of scientists with expertise in substance use disorders (SUD) and genetic methodologies primarily to determine the feasibility of performing whole genome...
4.
Cai N, Verhulst B, Andreassen O, Buitelaar J, Edenberg H, Hettema J, et al.
Mol Psychiatry
. 2025 Jan;
PMID: 39875590
No abstract available.
5.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature
. 2025 Jan;
PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
6.
Davis C, Jinwala Z, Hatoum A, Toikumo S, Agrawal A, Rentsch C, et al.
JAMA Netw Open
. 2025 Jan;
8(1):e2453913.
PMID: 39786773
Importance: Recently, the US Food and Drug Administration gave premarketing approval to an algorithm based on its purported ability to identify individuals at genetic risk for opioid use disorder (OUD)....
7.
Cai N, Verhulst B, Andreassen O, Buitelaar J, Edenberg H, Hettema J, et al.
Mol Psychiatry
. 2024 Dec;
PMID: 39730880
Psychiatric disorders are highly comorbid, heritable, and genetically correlated [1-4]. The primary objective of cross-disorder psychiatric genetics research is to identify and characterize both the shared genetic factors that contribute...
8.
Li X, Liu J, Boreland A, Kapadia S, Zhang S, Stillitano A, et al.
Sci Adv
. 2024 Nov;
10(45):eado5820.
PMID: 39514655
Polygenic risk scores (PRSs) assess genetic susceptibility to alcohol use disorder (AUD), yet their molecular implications remain underexplored. Neuroimmune interactions, particularly in microglia, are recognized as notable contributors to AUD...
9.
Hatoum A, Davis C, Kember R, Johnstone M, Oslin D, Zinkstok J, et al.
Lancet Psychiatry
. 2024 Oct;
12(2):94-95.
PMID: 39413801
No abstract available.
10.
Green N, Gao H, Chu X, Yuan Q, McGuire P, Lai D, et al.
bioRxiv
. 2024 Aug;
PMID: 39149227
Alcohol use disorder (AUD) induces complex transcriptional and regulatory changes across multiple brain regions including the caudate nucleus, which remains understudied. Using paired single-nucleus RNA-seq and ATAC-seq on caudate samples...