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Adam X Maihofer

Explore the profile of Adam X Maihofer including associated specialties, affiliations and a list of published articles. Areas
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Articles 86
Citations 2123
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Recent Articles
1.
Lee Y, Zhang Y, Espinosa Dice A, Li J, Tubbs J, Feng Y, et al.
medRxiv . 2025 Mar; PMID: 40061358
Importance: Biomarkers can potentially improve the diagnosis, monitoring, and treatment of posttraumatic stress disorder (PTSD). However, PTSD biomarkers that are scalable and easily integrated into real-world clinical settings have not...
2.
Schwaba T, Mallard T, Maihofer A, Rhemtulla M, Lee P, Smoller J, et al.
Nat Genet . 2025 Mar; 57(3):583-590. PMID: 40055480
Differences in the patterning of genetic sharing between groups of individuals may arise from biological pathways, social mechanisms, phenotyping and ascertainment. We expand genomic structural equation modeling to allow for...
3.
Mishra H, Wei H, LeRoux M, Ko D, Rohr K, Nievergelt C, et al.
FEBS J . 2025 Feb; PMID: 39995020
Bipolar disorder (BD) is characterized by disrupted circadian rhythms and neuronal loss. Lithium amplifies circadian rhythms and is neuroprotective, indicating mechanistic overlap across cellular systems. We examined the role of...
4.
OConnell K, Koromina M, van der Veen T, Boltz T, David F, Yang J, et al.
Nature . 2025 Jan; PMID: 39843750
Bipolar disorder is a leading contributor to the global burden of disease. Despite high heritability (60-80%), the majority of the underlying genetic determinants remain unknown. We analysed data from participants...
5.
Honorato-Mauer J, Shah N, Maihofer A, Zai C, Belangero S, Nievergelt C, et al.
Am J Hum Genet . 2025 Jan; 112(2):224-234. PMID: 39753130
In recent years, significant efforts have been made to improve methods for genomic studies of admixed populations using local ancestry inference (LAI). Accurate LAI is crucial to ensure that downstream...
6.
Katrinli S, Wani A, Maihofer A, Ratanatharathorn A, Daskalakis N, Montalvo-Ortiz J, et al.
Genome Med . 2024 Dec; 16(1):147. PMID: 39696436
Background: The occurrence of post-traumatic stress disorder (PTSD) following a traumatic event is associated with biological differences that can represent the susceptibility to PTSD, the impact of trauma, or the...
7.
Morey R, Zheng Y, Bayly H, Sun D, Garrett M, Gasperi M, et al.
Transl Psychiatry . 2024 Oct; 14(1):451. PMID: 39448598
Genetic contributions to human cortical structure manifest pervasive pleiotropy. This pleiotropy may be harnessed to identify unique genetically-informed parcellations of the cortex that are neurobiologically distinct from functional, cytoarchitectural, or...
8.
Pathak G, Wendt F, Maihofer A, Ressler K, Stein M, Koenen K, et al.
Am J Psychiatry . 2024 Oct; 181(12):1127-1130. PMID: 39380377
No abstract available.
9.
Wani A, Katrinli S, Zhao X, Daskalakis N, Zannas A, Aiello A, et al.
BMC Med Genomics . 2024 Sep; 17(1):235. PMID: 39334086
Background: Incorporating genomic data into risk prediction has become an increasingly popular approach for rapid identification of individuals most at risk for complex disorders such as PTSD. Our goal was...
10.
Honorato-Mauer J, Shah N, Maihofer A, Zai C, Belangero S, Nievergelt C, et al.
bioRxiv . 2024 Sep; PMID: 39253486
In recent years, significant efforts have been made to improve methods for genomic studies of admixed populations using Local Ancestry Inference (LAI). Accurate LAI is crucial to ensure downstream analyses...