Chouaib Tahtaoui
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Explore the profile of Chouaib Tahtaoui including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Tahtaoui C, Demailly A, Guidemann C, Joyeux C, Schneider P
J Org Chem
. 2010 May;
75(11):3781-5.
PMID: 20446707
Both enantiomers of the DHFR inhibitor iclaprim (R)-1 and (S)-1 were synthesized from the cyclopropyl homoallyl alcohols (R)-6 and (S)-6, respectively. As key steps these transformations include a Mitsunobu reaction...
2.
Tahtaoui C, Thomas C, Rohmer F, Klotz P, Duportail G, Mely Y, et al.
J Org Chem
. 2006 Dec;
72(1):269-72.
PMID: 17194109
A straightforward method for the synthesis of original 4,4-dialkoxy- or 4,4-diaryloxy-diaza-s-indacenes (BODIPY) derivatives obtained by treatment of BODIPY 1 with various alcohols in the presence of AlCl3 is described. The...
3.
Tahtaoui C, Guillier F, Klotz P, Galzi J, Hibert M, Ilien B
J Med Chem
. 2005 Nov;
48(24):7847-59.
PMID: 16302823
The efficiency of fluorescence resonance energy transfer (FRET) is dependent upon donor-acceptor proximity and spectral overlap, whether the acceptor partner is fluorescent or not. We report here on the design,...
4.
Fluorescent pirenzepine derivatives as potential bitopic ligands of the human M1 muscarinic receptor
Tahtaoui C, Parrot I, Klotz P, Guillier F, Galzi J, Hibert M, et al.
J Med Chem
. 2004 Aug;
47(17):4300-15.
PMID: 15294002
Following a recent description of fluorescence resonance energy transfer between enhanced green fluorescent protein (EGFP)-fused human muscarinic M1 receptors and Bodipy-labeled pirenzepine, we synthesized seven fluorescent derivatives of this antagonist...
5.
Tahtaoui C, Balestre M, Klotz P, Rognan D, Barberis C, Mouillac B, et al.
J Biol Chem
. 2003 Jul;
278(41):40010-9.
PMID: 12869559
To identify the binding site of the human V1a vasopressin receptor for the selective nonpeptide antagonist SR49059, we have developed a site-directed irreversible labeling strategy that combines mutagenesis of the...