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Chloe K Boehm

Explore the profile of Chloe K Boehm including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 813
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Recent Articles
1.
Arizti-Sanz J, Bradley A, Zhang Y, Boehm C, Freije C, Grunberg M, et al.
Nat Biomed Eng . 2022 May; 6(8):932-943. PMID: 35637389
The widespread transmission and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) call for rapid nucleic acid diagnostics that are easy to use outside of centralized clinical laboratories. Here...
2.
Arizti-Sanz J, Bradley A, Zhang Y, Boehm C, Freije C, Grunberg M, et al.
medRxiv . 2021 Nov; PMID: 34751276
The COVID-19 pandemic, and the recent rise and widespread transmission of SARS-CoV-2 Variants of Concern (VOCs), have demonstrated the need for ubiquitous nucleic acid testing outside of centralized clinical laboratories....
3.
Botti-Lodovico Y, Nair P, Nosamiefan D, Stremlau M, Schaffner S, Agignoae S, et al.
Viruses . 2021 Aug; 13(8). PMID: 34452470
While investigating a signal of adaptive evolution in humans at the gene LARGE, we encountered an intriguing finding by Dr. Stefan Kunz that the gene plays a critical role in...
4.
Arizti-Sanz J, Freije C, Stanton A, Petros B, Boehm C, Siddiqui S, et al.
Nat Commun . 2020 Nov; 11(1):5921. PMID: 33219225
The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for controlling disease transmission. Here, we develop SHINE (Streamlined Highlighting of Infections to Navigate Epidemics), a sensitive and specific...
5.
Barnes K, Lachenauer A, Nitido A, Siddiqui S, Gross R, Beitzel B, et al.
Nat Commun . 2020 Aug; 11(1):4131. PMID: 32807807
Recent outbreaks of viral hemorrhagic fevers (VHFs), including Ebola virus disease (EVD) and Lassa fever (LF), highlight the urgent need for sensitive, deployable tests to diagnose these devastating human diseases....
6.
Arizti-Sanz J, Freije C, Stanton A, Boehm C, Petros B, Siddiqui S, et al.
bioRxiv . 2020 Jun; PMID: 32511415
The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for controlling disease transmission. Here, we develop SHINE (SHERLOCK and HUDSON Integration to Navigate Epidemics), a sensitive and specific...
7.
Ackerman C, Myhrvold C, Thakku S, Freije C, Metsky H, Yang D, et al.
Nature . 2020 Apr; 582(7811):277-282. PMID: 32349121
The great majority of globally circulating pathogens go undetected, undermining patient care and hindering outbreak preparedness and response. To enable routine surveillance and comprehensive diagnostic applications, there is a need...
8.
Freije C, Myhrvold C, Boehm C, Lin A, Welch N, Carter A, et al.
Mol Cell . 2019 Oct; 76(5):826-837.e11. PMID: 31607545
The CRISPR effector Cas13 could be an effective antiviral for single-stranded RNA (ssRNA) viruses because it programmably cleaves RNAs complementary to its CRISPR RNA (crRNA). Here, we computationally identify thousands...
9.
Sirbulescu R, Boehm C, Soon E, Wilks M, Ilies I, Yuan H, et al.
Wound Repair Regen . 2017 Sep; 25(5):774-791. PMID: 28922523
Chronic wounds affect 12-15% of patients with diabetes and are associated with a drastic decrease in their quality of life. Here, we demonstrate that purified mature naive B220 /CD19 /IgM...