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Chinnaswamy Jagannath

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Articles 75
Citations 6172
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Recent Articles
11.
Sayedahmed E, Araujo M, Silva-Pereira T, Chothe S, Elkashif A, Alhashimi M, et al.
Mol Ther Methods Clin Dev . 2023 Jul; 30:194-207. PMID: 37502665
Because of continual generation of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it is critical to design the next generation of vaccines to combat the threat posed...
12.
Sarkar S, Mishra A, Periasamy S, Dyett B, Dogra P, Ball A, et al.
ACS Appl Mater Interfaces . 2023 Jun; 15(23):27670-27686. PMID: 37262346
An improved vaccine is urgently needed to replace the now more than 100-year-old Bacillus Calmette-Guérin (BCG) vaccine against tuberculosis (TB) disease, which represents a significant burden on global public health....
13.
Zhang K, Sowers M, Cherryhomes E, Singh V, Mishra A, Restrepo B, et al.
Front Immunol . 2023 Mar; 14:1121495. PMID: 36993975
Macrophages are the preeminent phagocytic cells which control multiple infections. Tuberculosis a leading cause of death in mankind and the causative organism (MTB) infects and persists in macrophages. Macrophages use...
14.
Sowers M, Tang H, Singh V, Khan A, Mishra A, Restrepo B, et al.
J Biol Chem . 2022 Aug; 298(10):102418. PMID: 36030823
Macrophages (MФ) are an essential immune cell for defense and repair that travel to different tissues and adapt based on local stimuli. A critical factor that may govern their polarization...
15.
Singh V, Chau E, Mishra A, DeAnda A, Hegde V, Sastry J, et al.
J Control Release . 2022 Aug; 349:796-811. PMID: 35914613
We describe a role of CD44-mediated signaling during host-defense against tuberculosis (TB) using a mouse model of TB and studies in M. tuberculosis (Mtb) infected human macrophage (MФ). Liposomes targeting...
16.
Singh V, Khan A, Xu Y, Mai S, Zhang L, Mishra A, et al.
Front Immunol . 2022 Jun; 13:865503. PMID: 35757769
Tuberculosis is a leading cause of death in mankind due to infectious agents, and (Mtb) infects and survives in macrophages (MФs). Although MФs are a major niche, myeloid-derived suppressor cells...
17.
Mishra A, Singh V, Jagannath C, Subbian S, Restrepo B, Gauduin M, et al.
Front Immunol . 2022 May; 13:859116. PMID: 35634283
GM-CSF is an important cytokine that regulates the proliferation of monocytes/macrophages and its various functions during health and disease. Although growing evidences support the notion that GM-CSF could play a...
18.
Khan A, Zhang K, Singh V, Mishra A, Kachroo P, Bing T, et al.
Commun Biol . 2022 May; 5(1):480. PMID: 35590096
Mycobacterium tuberculosis (Mtb) is responsible for approximately 1.5 million deaths each year. Though 10% of patients develop tuberculosis (TB) after infection, 90% of these infections are latent. Further, mice are ...
19.
Jagannath C, McBride J, Vergne I
Front Immunol . 2021 Oct; 12:768935. PMID: 34650572
No abstract available.
20.
Khan A, Sayedahmed E, Singh V, Mishra A, Dorta-Estremera S, Nookala S, et al.
Cell Rep Med . 2021 Sep; 2(8):100372. PMID: 34467249
Although the BCG vaccine offers partial protection, tuberculosis remains a leading cause of infectious disease death, killing ∼1.5 million people annually. We developed mucosal vaccines expressing the autophagy-inducing peptide C5...