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Chih-Yuan Lee

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Articles 79
Citations 614
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Recent Articles
21.
Huang Y, Cao J, Lee C, Wu Y
Stem Cell Res Ther . 2021 Nov; 12(1):568. PMID: 34772443
Background: Cirrhosis is a chronic liver disease whereby scar tissue replaces healthy liver parenchyma, leading to disruption of the liver architecture and hepatic dysfunction. Currently, there is no effective disease-modifying...
22.
Kung P, Lai T, Cao J, Hsu L, Chiang T, Ou-Yang P, et al.
Cancer Immunol Immunother . 2021 Aug; 71(3):705-718. PMID: 34374812
Background: A major feature of the microenvironment in pancreatic ductal adenocarcinoma (PDAC) is the significant amount of extracellular matrix produced by pancreatic stellate cells (PSCs), which have been reported to...
23.
Yang Y, Chen C, Yang C, Lee C, Yang H, Chiang B, et al.
J Formos Med Assoc . 2021 Jul; 121(5):958-968. PMID: 34294497
Background/purpose: Hepatitis B surface antigen (HBsAg)-positive renal transplantation recipients must take lifelong immunosuppressants and nucleotide analogues (NAs). We investigated the cellular immune responses of HBsAg-positive renal transplantation recipients taking immunosuppressants...
24.
Perng D, Hung C, Lin H, Morgan P, Hsu Y, Wu T, et al.
BMC Cancer . 2021 Jul; 21(1):828. PMID: 34273969
Background: Autophagy-related proteins may predict postresection overall survival (OS) and disease-free survival (DFS) in patients with combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC). Methods: We prospectively investigated how these proteins affect...
25.
Tien Y, Chien H, Chiang T, Chung M, Lee C, Peng S, et al.
Diabetologia . 2021 Jul; 64(10):2266-2278. PMID: 34272581
Aims/hypothesis: Islets are thought to be stably present in the adult human pancreas to maintain glucose homeostasis. However, identification of the pancreatic intraepithelial neoplasia (PanIN)-islet complex in mice and the...
26.
Lin C, Shen Y, Chang C, Guo X, Young Y, Lai T, et al.
Nat Commun . 2021 Jun; 12(1):3878. PMID: 34188032
Different levels of regulatory mechanisms, including posttranscriptional regulation, are needed to elaborately regulate inflammatory responses to prevent harmful effects. Terminal uridyltransferase 7 (TUT7) controls RNA stability by adding uridines to...
27.
Shen C, Chou C, Lai T, Hsu J, Lin Y, Liu H, et al.
Front Cell Dev Biol . 2021 May; 9:642625. PMID: 33996800
Activation of the epidermal growth factor receptor (EGFR) is crucial for development, tissue homeostasis, and immunity. Dysregulation of EGFR signaling is associated with numerous diseases. EGFR ubiquitination and endosomal trafficking...
28.
Chen Y, Hsieh P, Lin H, Hung C, Lo G, Hsu Y, et al.
BMC Gastroenterol . 2021 May; 21(1):220. PMID: 33990184
Background: The benefits of surgical resection (SR) for various Barcelona Clinic Liver Cancer (BCLC) stages of hepatocellular carcinoma (HCC) remain unclear. We investigated the risk factors of overall survival (OS)...
29.
Chen C, Peng S, Wu P, Chien H, Lee C, Chung M, et al.
Am J Physiol Endocrinol Metab . 2021 Apr; 320(6):E1007-E1019. PMID: 33900850
Intraportal islet transplantation has been clinically applied for treatment of unstable type 1 diabetes. However, in the liver, systematic assessment of the dispersed islet grafts and the graft-hepatic integration remains...
30.
Ding M, Lee C, Wang Y, Hsu C, Tsai Y, Tsai M
Int J Surg Case Rep . 2021 Feb; 80:105620. PMID: 33592426
Introduction: Deep neck infection is a life-threatening disease that invades deep neck space and potentially causes airway obstruction. Treatment for deep neck infection consists of antibiotic administration and surgical drainage...