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Ting-Yu Lai

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Articles 29
Citations 284
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Recent Articles
1.
Lai Z, Yang C, Chen P, Chen W, Lai T, Lu G, et al.
Mol Biol Rep . 2024 May; 51(1):604. PMID: 38700644
Background: The healing process after a myocardial infarction (MI) in humans involves complex events that replace damaged tissue with a fibrotic scar. The affected cardiac tissue may lose its function...
2.
Lai T, Chiang T, Lee C, Kuo T, Wu C, Chen Y, et al.
Br J Cancer . 2024 Feb; 130(7):1096-1108. PMID: 38341509
Background: Pancreatic neuroendocrine tumors (PNETs) with low microvessel density and fibrosis often exhibit clinical aggressiveness. Given the contribution of cancer-associated fibroblasts (CAFs) to the hypovascular fibrotic stroma in pancreatic ductal...
3.
Lai T, Ko Y, Chen Y, Lin S
Biomedicines . 2023 Jun; 11(6). PMID: 37371812
Identifying and treating tumors early is the key to secondary prevention in cancer control. At present, prevention of oral cancer is still challenging because the molecular drivers responsible for malignant...
4.
Lin Y, Chang Y, Chao T, Tsai Y, Jhuang S, Ho Y, et al.
J Exp Med . 2023 May; 220(8). PMID: 37158982
Type I interferons are important antiviral cytokines, but prolonged interferon production is detrimental to the host. The TLR3-driven immune response is crucial for mammalian antiviral immunity, and its intracellular localization...
5.
Lai T, Averkiou M
Ultrasound Med Biol . 2022 Nov; 49(1):186-202. PMID: 36441029
Amplitude modulation (AM) suppresses tissue signals and detects microbubble signals in contrast-enhanced ultrasound (CEUS) and is often implemented with checkerboard apertures. However, possible crosstalk between transmitting and non-transmitting array elements...
6.
Lai T, Cao J, Ou-Yang P, Tsai C, Lin C, Chen C, et al.
Sci Rep . 2022 Apr; 12(1):5713. PMID: 35383242
In cell culture environment, some cells adhere firmly to the culture plates and may be vulnerable to cell detachment during passage. Therefore, it is important to harvest cells with a...
7.
Keller S, Lai T, De Koninck L, Averkiou M
IEEE Trans Ultrason Ferroelectr Freq Control . 2022 Jan; 69(3):1032-1040. PMID: 35073259
Contrast-enhanced ultrasound (CEUS) imaging relies on distinguishing between microbubble and tissue echoes. Amplitude modulation (AM), a nonlinear pulsing scheme, has been developed to take advantage of the amplitude-dependent nonlinearity of...
8.
Liu Y, Chen Y, Lai T, Ko Y, Chou Y, Chen P, et al.
Front Oncol . 2021 Dec; 11:769665. PMID: 34869001
Background: Partial epithelial-mesenchymal transition (p-EMT) is a distinct clinicopathological feature prevalent in oral cavity tumors of The Cancer Genome Atlas. Located at the invasion front, p-EMT cells require additional support...
9.
Kung P, Lai T, Cao J, Hsu L, Chiang T, Ou-Yang P, et al.
Cancer Immunol Immunother . 2021 Aug; 71(3):705-718. PMID: 34374812
Background: A major feature of the microenvironment in pancreatic ductal adenocarcinoma (PDAC) is the significant amount of extracellular matrix produced by pancreatic stellate cells (PSCs), which have been reported to...
10.
Lin C, Shen Y, Chang C, Guo X, Young Y, Lai T, et al.
Nat Commun . 2021 Jun; 12(1):3878. PMID: 34188032
Different levels of regulatory mechanisms, including posttranscriptional regulation, are needed to elaborately regulate inflammatory responses to prevent harmful effects. Terminal uridyltransferase 7 (TUT7) controls RNA stability by adding uridines to...