Chih-Wei Fan
Overview
Explore the profile of Chih-Wei Fan including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
8
Citations
895
Followers
0
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Related Specialties
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Recent Articles
1.
Wu X, Zhang L, Toombs J, Kuo Y, Tyler Piazza J, Tuladhar R, et al.
Nat Cell Biol
. 2017 Sep;
19(10):1226-1236.
PMID: 28945232
Direct interactions between pro- and anti-apoptotic BCL-2 family members form the basis of cell death decision-making at the outer mitochondrial membrane (OMM). Here we report that three anti-apoptotic BCL-2 proteins...
2.
Fan C, Chen B, Franco I, Lu J, Shi H, Wei S, et al.
Chem Biol
. 2017 Sep;
22(4):559.
PMID: 28934606
No abstract available.
3.
Fan C, Chen B, Franco I, Lu J, Shi H, Wei S, et al.
Chem Biol
. 2014 Dec;
21(12):1680-9.
PMID: 25484239
Misactivation of the seven-transmembrane protein Smoothened (Smo) is frequently associated with basal cell carcinoma and medulloblastoma. Cellular exposure to secreted Hedgehog (Hh) protein or oncogenic mutations in Hh pathway components...
4.
Fan C, Tuladhar R, Lum L
Nat Chem Biol
. 2013 Mar;
9(4):217-8.
PMID: 23508185
No abstract available.
5.
Gao S, Wang Q, Wang G, Lomenick B, Liu J, Fan C, et al.
Synlett
. 2012 Dec;
16(23):2298-2310.
PMID: 23226922
Isolated from the sponge Terpios hoshinota that causes coral black disease, nakiterpiosin was the first C-nor-D-homosteroid discovered from a marine source. We provide in this account an overview of the...
6.
Jacob L, Wu X, Dodge M, Fan C, Kulak O, Chen B, et al.
Sci Signal
. 2011 Jan;
4(157):ra4.
PMID: 21266715
The Hedgehog (Hh) and Wnt signal transduction pathways are master regulators of embryogenesis and tissue renewal and represent anticancer therapeutic targets. Using genome-wide RNA interference screening in murine cultured cells,...
7.
Lu J, Ma Z, Hsieh J, Fan C, Chen B, Longgood J, et al.
Bioorg Med Chem Lett
. 2009 May;
19(14):3825-7.
PMID: 19410457
Suppression of oncogenic Wnt-mediated signaling holds promise as an anti-cancer therapeutic strategy. We previously reported a novel class of small molecules (IWR-1/2, inhibitors of Wnt response) that antagonize Wnt signaling...
8.
Chen B, Dodge M, Tang W, Lu J, Ma Z, Fan C, et al.
Nat Chem Biol
. 2009 Jan;
5(2):100-7.
PMID: 19125156
The pervasive influence of secreted Wnt signaling proteins in tissue homeostasis and tumorigenesis has galvanized efforts to identify small molecules that target Wnt-mediated cellular responses. By screening a diverse synthetic...