Chih-Chung Tseng
Overview
Explore the profile of Chih-Chung Tseng including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
110
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Griffiths K, Grand R, Horan I, Certo M, Keeler R, Mauro C, et al.
Vascul Pharmacol
. 2024 Jun;
156:107399.
PMID: 38901807
Increased proliferation and reduced apoptosis of pulmonary artery smooth muscle cells (PASMCs) is recognised as a universal hallmark of pulmonary arterial hypertension (PAH), in part related to the association with...
2.
Zhai D, Yan S, Samsom J, Wang L, Su P, Jiang A, et al.
Sci Adv
. 2023 Dec;
9(49):eadj6187.
PMID: 38064562
While most research and treatments for multiple sclerosis (MS) focus on autoimmune reactions causing demyelination, it is possible that neurodegeneration precedes the autoimmune response. Hence, glutamate receptor antagonists preventing excitotoxicity...
3.
Tseng C, Baillie G, Donvito G, Mustafa M, Juola S, Zanato C, et al.
J Med Chem
. 2019 May;
62(10):5049-5062.
PMID: 31050898
The first generation of CB positive allosteric modulators (e.g., ZCZ011) featured a 3-nitroalkyl-2-phenyl-indole structure. Although a small number of drugs include the nitro group, it is generally not regarded as...
4.
Phyu S, Tseng C, Smith T
MAGMA
. 2018 Nov;
32(2):227-235.
PMID: 30446846
Purpose: Glycogen synthase kinase 3 (GSK3) is a key controlling element of many cellular processes including cell-cycle progression and recent studies suggest that GSK3 is a potential anticancer target. Changes...
5.
Tyagi R, Maddirala A, Elfawal M, Fischer C, Bulman C, Rosa B, et al.
ACS Infect Dis
. 2018 May;
4(7):1130-1145.
PMID: 29718656
The enormous prevalence of infections caused by parasitic nematodes worldwide, coupled to the rapid emergence of their resistance to commonly used anthelmintic drugs, presents an urgent need for the discovery...
6.
Smith T, Phyu S, Alzyoud K, Tseng C
Biomed Res Int
. 2017 Jul;
2017:4793465.
PMID: 28717648
Androgen receptor (AR) activation is the primary driving factor in prostate cancer which is initially responsive to castration but then becomes resistant (castration-resistant prostate cancer (CRPC)). CRPC cells still retain...
7.
Tseng C, Noordali H, Sani M, Madhani M, Grant D, Frenneaux M, et al.
J Med Chem
. 2017 Mar;
60(7):2780-2789.
PMID: 28277663
We designed and synthesized perhexiline analogues that have the same therapeutic profile as the parent cardiovascular drug but lacking its metabolic liability associated with CYP2D6 metabolism. Cycloalkyl perhexiline analogues 6a-j...
8.
Phyu S, Tseng C, Fleming I, Smith T
Sci Rep
. 2016 Nov;
6:36544.
PMID: 27811956
Akt is an intracellular signalling pathway that serves as an essential link between cell surface receptors and cellular processes including proliferation, development and survival. The pathway has many downstream targets...
9.
He C, Zhu C, Dai Z, Tseng C, Ding H
Angew Chem Int Ed Engl
. 2013 Nov;
52(50):13256-60.
PMID: 24174294
No abstract available.
10.
Maiti B, Chanda K, Selvaraju M, Tseng C, Sun C
ACS Comb Sci
. 2013 Apr;
15(6):291-7.
PMID: 23590286
A novel one-pot, three-component reaction employing variously substituted benzimidazole-linked amino pyridines, aldehydes, and isonitriles catalyzed by scandium(III) triflate under solvent-free conditions were accomplished. This new synthetic methodology facilitates the rapid...