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Chih-Chung Tseng

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Articles 21
Citations 110
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Recent Articles
11.
Tseng C, Tasi C, Sun C
Comb Chem High Throughput Screen . 2012 Jan; 15(5):411-7. PMID: 22263891
A novel protocol for rapid assemble of benzimidazole framework has been demonstrated. This method incorporated with light fluorous-tag provides a convenient method for diversification of benzimidazoles and for easy purification...
12.
Chanda K, Maiti B, Tseng C, Sun C
ACS Comb Sci . 2012 Jan; 14(2):115-23. PMID: 22263632
A novel and efficient diversity-oriented synthetic approach was employed to access the benzo[d]oxazol-5-yl-1H-benzo[d]imidazole on ionic liquid support, which helps to absorb microwave irradiation. In this paper, we successfully coupled 4-hydroxy-3-nitrobenzoic...
13.
Pouwer R, Richard J, Tseng C, Chen D
Chem Asian J . 2011 Dec; 7(1):22-35. PMID: 22162365
In the long lasting battle against cancer, Nature sometimes gives a helping hand to researchers to find new drugs for the treatment of diseases and improvement of patients' well-being. Englerin...
14.
Tseng C, Ding H, Li A, Guan Y, Chen D
Org Lett . 2011 Jul; 13(16):4410-3. PMID: 21770370
A modular strategy leading to the salvileucalin B core structure has been accomplished. The developed synthetic strategy featured a bioinspired intramolecular Diels-Alder reaction to construct domain "A", REDOX chemistry to...
15.
Peixoto P, Severin R, Tseng C, Chen D
Angew Chem Int Ed Engl . 2011 Mar; 50(13):3013-6. PMID: 21404388
No abstract available.
16.
Spivey A, Tseng C
Methods Enzymol . 2010 Nov; 485:499-525. PMID: 21050934
Rimonabant (acomplia) is a 1,5-diarylpyrazole derivative that acts as a type 1 cannabinoid receptor (CB₁) inverse agonist. Here, we overview the role of this type of molecule in regulation of...
17.
Chung T, Yang M, Tseng C, Sheu S, Wang S, Huang Y, et al.
Biomaterials . 2010 Oct; 32(3):734-43. PMID: 20888633
Poly(ε-caprolactone) (PCL) scaffolds were modified by grafting nerve growth factor (NGF) and Tirofiban (TF), a clinical anti-thrombosis drug, as a new biomaterial for producing nerve conduits to promote the regeneration...
18.
Chen D, Tseng C
Org Biomol Chem . 2010 May; 8(13):2900-11. PMID: 20463995
Synthetic efforts culminating the construction of several highly advanced intermediates, and completed syntheses of the recently disclosed cortistatin family of anti-proliferative agents are described in this perspective.
19.
Spivey A, Tseng C, Jones T, Kohler A, Ellames G
Org Lett . 2009 Sep; 11(20):4760-3. PMID: 19778010
A method for the parallel solid-phase synthesis (SPS) of iodinated analogues of Sanofi-Aventis' type 1 cannabinoid (CB1) receptor inverse agonist rimonabant (acomplia) has been developed. The method allows the synthesis...
20.
Spivey A, Martin L, Tseng C, Ellames G, Kohler A
Org Biomol Chem . 2008 Oct; 6(22):4093-5. PMID: 18972036
Syntheses of two 4-phenylpiperidines from bromobenzene have been developed involving anchoring to a fluorous-tag, Ir-catalysed borylation, Pd- and Co-catalysed elaboration then traceless cleavage. Although performed using 'cold' (i.e. unlabelled) bromobenzene...