Chih-Chin Shih
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Explore the profile of Chih-Chin Shih including associated specialties, affiliations and a list of published articles.
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32
Citations
204
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Recent Articles
1.
Wu J, Lohelaid H, Shih C, Liew H, Wang V, Hu W, et al.
Mol Ther
. 2024 Sep;
32(11):4021-4044.
PMID: 39256999
Cerebral reperfusion injury in stroke, stemming from interconnected thrombotic and inflammatory signatures, often involves platelet activation, aggregation and its interaction with various immune cells, contributing to microvascular dysfunction. However, the...
2.
Ke H, Chen J, Kao S, Tsao C, Kuo C, Wu C, et al.
Thromb Res
. 2024 Jul;
241:109091.
PMID: 38986215
Introduction: Heatstroke is a critical heat-related condition characterized by coagulopathy and multiple organ dysfunction. One of the most severe complications of heatstroke is disseminated intravascular coagulation. This condition manifests as...
3.
Kao S, Tsao C, Ke H, Chou M, Wu C, Shih C
Thromb Res
. 2024 Jun;
241:109072.
PMID: 38945093
Introduction: Dysregulated host response to infection causes life-threatening organ dysfunction. Excessive inflammation and abnormal blood coagulation can lead to disseminated intravascular coagulation (DIC) and multiple-organ failure in the late sepsis...
4.
Ahmetaj-Shala B, Olanipekun M, Tesfai A, MacCallum N, Kirkby N, Quinlan G, et al.
Sci Rep
. 2024 May;
14(1):11800.
PMID: 38782945
No abstract available.
5.
Shih C, Liao W, Ke H, Kuo C, Tsao C, Tsai W, et al.
Biomed Pharmacother
. 2023 Mar;
161:114565.
PMID: 36958193
Global warming increases the incidence of heat stroke (HS) and HS causes the reduction of visceral blood flow during hyperthermia, leading to intestinal barrier disruption, microbial translocation, systemic inflammation and...
6.
Shih C, Chen S, Chang W, Tsai H, Huang H, Wu C, et al.
J Chin Med Assoc
. 2023 Mar;
86(7):688-695.
PMID: 36872476
Background: Both inflammation and oxidative stress contribute to the pathogenesis of sepsis and its associated organ damage. Angiotensin-(1-7), acting through the Mas receptor and angiotensin II-type 2 receptors (AT2R), could...
7.
Hii H, Lo W, Fu Y, Chen M, Shih C, Tsao C, et al.
Life Sci
. 2022 Oct;
310:121039.
PMID: 36209832
Aims: Heat stroke is a life-threatening disorder triggered by thermoregulatory failure. Hyperthermia-induced splanchnic hypoperfusion has been reported to induce intestinal barrier dysfunction and systemic immune response that ultimately cause multiple-organ...
8.
Tsai H, Chian C, Shih C, Chen S, Liaw W, Huang H, et al.
J Surg Res
. 2022 Jul;
279:526-532.
PMID: 35868036
Introduction: Sepsis and related complications lead to high morbidity and mortality in humans and animals. Olmesartan medoxomil (OLM), a nonpeptide angiotensin II type 1 receptor blocker, has antiinflammatory and antioxidative...
9.
Shih C, Chan M, Kirkby N, Vojnovic I, Mitchell J, Armstrong P, et al.
Br J Pharmacol
. 2021 Aug;
178(23):4758-4771.
PMID: 34383973
Background And Purpose: P2Y receptor antagonists reduce platelet aggregation and the incidence of arterial thrombosis. Adenosine signalling in platelets directly affects cyclic nucleotide tone, which we have shown to have...
10.
Tsai H, Shih C, Chang K, Liao M, Liaw W, Wu C, et al.
Sci Rep
. 2021 Jan;
11(1):610.
PMID: 33436885
Sepsis can lead to shock, multiple organ failure, and even death. Platelets play an active role in the pathogenesis of sepsis-induced multiple organ failure. Angiotensin (Ang)-(1-7), a biologically active peptide,...