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Chih-Chieh Shen

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Articles 8
Citations 31
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Recent Articles
1.
Kuan T, Shen C, Chen J, Tu K, Tsao C, Chen T
Nucl Med Commun . 2021 Dec; 43(1):17-23. PMID: 34887367
Objective: We used dynamic single-photon emission computed tomography (D-SPECT) to overcome the interference of the planar dynamic imaging due to the overlap of internal organs, thus more accurate physiological function...
2.
Wu C, Tang J, Chan P, Li J, Lin M, Shen C, et al.
Mol Imaging Biol . 2016 Oct; 19(3):408-420. PMID: 27730471
Purpose: Surgical resection is the standard treatment for localized colorectal cancer, which is the most common type of gastrointestinal cancer. However, over 40 % cases are diagnosed metastasized and apparently...
3.
Chang C, Chang C, Lo Y, Lin M, Shen C, Liu R, et al.
Bioorg Med Chem Lett . 2016 Jul; 26(16):4133-9. PMID: 27445169
Melanin is an attractive target for the diagnosis and treatment of malignant melanoma. Previous studies have demonstrated the specific binding ability of benzamide moiety to melanin. In this study, we...
4.
Chang C, Chang C, Shen C, Chen C, Liu R, Lin M, et al.
Eur J Pharm Sci . 2015 Nov; 81:201-9. PMID: 26517961
Melanin is an attractive target for the diagnosis and treatment of malignant melanoma. This study reports the preparation and biological characterizations of N-(2-(diethylamino)ethyl)-2-(3-(123/131)I-iodo-4- hydroxyphenyl)acetamide and N-(2-(diethylamino)ethyl)-3-(3-(123/131)I-iodo-4-hydroxyphenyl)propanamide (123/131)I-IHPA and 123/131I-IHPP) as...
5.
Chang C, Chang C, Shen C, Chen C, Liu R, Lin M, et al.
Bioorg Med Chem . 2015 Mar; 23(9):2261-9. PMID: 25800432
Malignant melanoma expresses a highly aggressive metastasis. Early diagnosis of malignant melanoma is important for patient survival. Radiolabeled benzamides and nicotinamides have been reported to be attractive candidates for malignant...
6.
Wu S, Huang S, Lo Y, Liu R, Wang S, Lin W, et al.
Biomed Res Int . 2014 Sep; 2014:912498. PMID: 25254219
Introduction: Benzamide can specifically bind to melanoma cells. A 18F-labeled benzamide derivative, [18F]N-(2-diethylaminoethyl)-4-[2-(2-(2-fluoroethoxy) ethoxy)ethoxy]benzamide ([18F]FPBZA), was developed as a promising PET probe for primary and metastatic melanoma. Methods: [18F]FPBZA was...
7.
Chang W, Kuo W, Wu C, Lin C, Chan P, Shen C, et al.
Appl Radiat Isot . 2013 Apr; 77:166-73. PMID: 23602704
This study evaluated a radioiodinated deoxycytidine analog, (131)I-5-iodo-2'-deoxycytidine ([(131)I]ICdR), as a novel proliferation probe and compared it with (131)I-5-iodo-2'-deoxyuridine ([(131)I]IUdR) in a NG4TL4 sarcoma-bearing mouse model. As an imaging agent,...
8.
Wu C, Chou L, Chan P, Ho C, Lin M, Shen C, et al.
Mol Imaging Biol . 2012 Dec; 15(3):326-35. PMID: 23247923
Purpose: This study aims to demonstrate that 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) positron emission tomography (PET) is a promising modality for noninvasively monitoring the therapeutic efficacy of Doxisome(®) in a subcutaneous hepatoma mouse...