Chiea-Chuen Khor
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Explore the profile of Chiea-Chuen Khor including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Tay J, Wang W, Guan L, Dorajoo R, Khor C, Feng L, et al.
J Gerontol A Biol Sci Med Sci
. 2025 Jan;
PMID: 39869450
Deoxyribonucleic acid (DNA) methylation (DNAm) clocks estimate biological age according to DNA methylation. This study investigated the associations between measures of physical function and physical performance and ten DNAm clocks...
2.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
Nature
. 2024 Feb;
627(8003):347-357.
PMID: 38374256
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution...
3.
Zhang J, Ye Y, Dorajoo R, Khor C, Chang X, Yu H, et al.
J Nutr
. 2023 Nov;
154(1):252-260.
PMID: 38035998
Background: It remains unclear if adherence to the planetary healthy diet (PHD), designed to improve human and environmental health, is associated with better cognitive function in aging, and if this...
4.
Li M, Wang Y, Wang L, Meah W, Shi D, Heng K, et al.
J Am Soc Nephrol
. 2023 Oct;
34(11):1900-1913.
PMID: 37787447
Significance Statement: Genome-wide association studies have identified nearly 20 IgA nephropathy susceptibility loci. However, most nonsynonymous coding variants, particularly ones that occur rarely or at a low frequency, have not...
5.
Berry S, Espich S, Thuong N, Chang X, Dorajoo R, Khor C, et al.
bioRxiv
. 2023 Sep;
PMID: 37662190
One Sentence Summary: Aldehydes produced by host cells contribute to the control of bacterial infections.
6.
Tan V, Liu T, Arifin Z, Pak B, Tan A, Wong S, et al.
Clin Chem
. 2023 Jul;
69(8):881-889.
PMID: 37477572
Background: Current strategies for preimplantation genetic testing for aneuploidy or structural rearrangements (PGT-A/SR) rely mainly on next-generation sequencing (NGS) and microarray platforms, which are robust but require expensive instrumentation. We...
7.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
medRxiv
. 2023 Apr;
PMID: 37034649
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes. To characterise the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study...
8.
Chang X, Chua K, Ng F, Wang L, Liu J, Yuan J, et al.
Int J Obes (Lond)
. 2023 Feb;
47(5):358-364.
PMID: 36788305
Background: How obesity earlier in life impacts upon mobility dysfunctions in late life is not well understood. Pernicious effects of excess weight on the musculoskeletal system and mobility dysfunctions are...
9.
Lee N, Hum M, Ong P, Myint M, Ong E, Low K, et al.
Cancers (Basel)
. 2022 Aug;
14(15).
PMID: 35954343
The current understanding of genetic susceptibility factors for nasopharyngeal carcinoma (NPC) is still incomplete. To identify novel germline variants associated with NPC predisposition, we analysed whole-exome sequencing data from 119...
10.
Chang X, Zhou Y, Wang L, Liu J, Yuan J, Khor C, et al.
NPJ Aging
. 2022 Aug;
8(1):6.
PMID: 35927272
The genetic basis of overall healthy ageing, especially among the East-Asian population is understudied. We conducted a genome-wide association study among 1618 Singapore Chinese elderly participants (65 years or older)...