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Chiara Galber

Explore the profile of Chiara Galber including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 97
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Recent Articles
1.
Grandi M, Galber C, Gatto C, Nobile V, Pucci C, Schaldemose Nielsen I, et al.
Int J Mol Sci . 2024 Mar; 25(6). PMID: 38542395
Mitochondria are involved in multiple aspects of neurodevelopmental processes and play a major role in the pathogenetic mechanisms leading to neuro-degenerative diseases. Fragile-X-related disorders (FXDs) are genetic conditions that occur...
2.
Galber C, Fabbian S, Gatto C, Grandi M, Carissimi S, Acosta M, et al.
Cell Death Dis . 2023 Jan; 14(1):54. PMID: 36690622
The mitochondrial protein IF1 binds to the catalytic domain of the ATP synthase and inhibits ATP hydrolysis in ischemic tissues. Moreover, IF1 is overexpressed in many tumors and has been...
3.
Galber C, Minervini G, Cannino G, Boldrin F, Petronilli V, Tosatto S, et al.
Cell Rep . 2021 May; 35(6):109111. PMID: 33979610
The f subunit is localized at the base of the ATP synthase peripheral stalk. Its function in the human enzyme is poorly characterized. Because full disruption of its ATP5J2 gene...
4.
Galber C, Carissimi S, Baracca A, Giorgio V
Life (Basel) . 2021 Apr; 11(4). PMID: 33917760
Human diseases range from gene-associated to gene-non-associated disorders, including age-related diseases, neurodegenerative, neuromuscular, cardiovascular, diabetic diseases, neurocognitive disorders and cancer. Mitochondria participate to the cascades of pathogenic events leading to...
5.
Galber C, Acosta M, Minervini G, Giorgio V
Biol Chem . 2020 Aug; 401(11):1199-1214. PMID: 32769215
The mitochondrial ATP synthase is a multi-subunit enzyme complex located in the inner mitochondrial membrane which is essential for oxidative phosphorylation under physiological conditions. In this review, we analyse the...
6.
Galber C, Valente G, von Stockum S, Giorgio V
Methods Mol Biol . 2019 Jan; 1925:233-243. PMID: 30674031
In the presence of Ca, F-ATP synthase preparations eluted from Blue Native gels generate electrophysiological currents that are typical of an inner mitochondrial membrane mega-channel, the permeability transition pore. Here...
7.
Giorgio V, Schiavone M, Galber C, Carini M, Da Ros T, Petronilli V, et al.
Biochim Biophys Acta Bioenerg . 2018 Apr; 1859(9):901-908. PMID: 29694828
Idebenone is a hydrophilic short-chain coenzyme (Co) Q analogue, which has been used as a potential bypass of defective complex I in both Leber Hereditary Optic Neuropathy and OPA1-dependent Dominant...