Chia-Chi C Key
Overview
Explore the profile of Chia-Chi C Key including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
117
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Recent Articles
1.
Key C, Bishop A, Wang X, Zhao Q, Chen G, Quinn M, et al.
J Lipid Res
. 2020 May;
61(7):1075-1086.
PMID: 32430316
The glycerol phosphate pathway produces more than 90% of the liver triacylglycerol (TAG). LysoPA, an intermediate in this pathway, is produced by glycerol-3-phosphate acyltransferase. Glycerophosphodiester phosphodiesterase domain containing 3 (GDPD3),...
2.
Wang Z, Zhao Q, Nie Y, Yu Y, Misra B, Zabalawi M, et al.
iScience
. 2020 May;
23(5):101125.
PMID: 32428862
Increased flux of glucose through glycolysis is a hallmark of inflammatory macrophages and is essential for optimal effector functions. Solute carrier (SLC) 37A2 is an endoplasmic reticulum-anchored phosphate-linked glucose-6-phosphate transporter...
3.
Bashore A, Liu M, Key C, Boudyguina E, Wang X, Carroll C, et al.
Arterioscler Thromb Vasc Biol
. 2019 Jun;
39(9):1747-1761.
PMID: 31167565
Objective: The role of hepatocyte Abca1 (ATP binding cassette transporter A1) in trafficking hepatic free cholesterol (FC) into plasma versus bile for reverse cholesterol transport (RCT) is poorly understood. We...
4.
Cuffe H, Liu M, Key C, Boudyguina E, Sawyer J, Weckerle A, et al.
Arterioscler Thromb Vasc Biol
. 2018 Jan;
38(4):733-743.
PMID: 29348118
Objective: Adipose tissue cholesterol increases with adipocyte triglyceride content and size during development of obesity. However, how adipocyte cholesterol affects adipocyte function is poorly understood. The aim of this study...
5.
Shen L, Yang Y, Ou T, Key C, Tong S, Sequeira R, et al.
J Lipid Res
. 2017 Jul;
58(9):1808-1821.
PMID: 28729463
Dietary PUFAs reduce atherosclerosis and macrophage inflammation, but how nucleotide-binding oligomerization domain leucine-rich repeat-containing receptor protein (NLRP3) inflammasome activation and autophagy influence PUFA-mediated atheroprotection is poorly understood. We fed Ldlr...
6.
Key C, Liu M, Kurtz C, Chung S, Boudyguina E, Dinh T, et al.
Cell Rep
. 2017 Jun;
19(10):2116-2129.
PMID: 28591582
Plasma membrane (PM) free cholesterol (FC) is emerging as an important modulator of signal transduction. Here, we show that hepatocyte-specific knockout (HSKO) of the cellular FC exporter, ATP-binding cassette transporter...