Chew-Li Soh
Overview
Explore the profile of Chew-Li Soh including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
471
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Douvaras P, Buenaventura D, Sun B, Lepack A, Baker E, Simpson E, et al.
Nat Commun
. 2024 Sep;
15(1):8132.
PMID: 39284802
Mucopolysaccharidoses are inherited metabolic disorders caused by the deficiency in lysosomal enzymes required to break down glycosaminoglycans. Accumulation of glycosaminoglycans leads to progressive, systemic degenerative disease. The central nervous system...
2.
Kahraman S, Dirice E, Basile G, Diegisser D, Alam J, Johansson B, et al.
Nat Metab
. 2022 Jan;
4(1):76-89.
PMID: 35058633
MODY8 (maturity-onset diabetes of the young, type 8) is a dominantly inherited monogenic form of diabetes associated with mutations in the carboxyl ester lipase (CEL) gene expressed by pancreatic acinar...
3.
Li Q, Dixon G, Verma N, Rosen B, Gordillo M, Luo R, et al.
Nat Genet
. 2019 May;
51(6):999-1010.
PMID: 31110351
Human embryonic stem cells (ESCs) and human induced pluripotent stem cells hold great promise for cell-based therapies and drug discovery. However, homogeneous differentiation remains a major challenge, highlighting the need...
4.
Shi Z, Soh C, Zhu Z, Huangfu D
J Vis Exp
. 2017 Mar;
(121).
PMID: 28287608
Interrogating gene function in self-renewing or differentiating human pluripotent stem cells (hPSCs) offers a valuable platform towards understanding human development and dissecting disease mechanisms in a dish. To capitalize on...
5.
Shi Z, Lee K, Yang D, Amin S, Verma N, Li Q, et al.
Cell Stem Cell
. 2017 Feb;
20(5):675-688.e6.
PMID: 28196600
Human disease phenotypes associated with haploinsufficient gene requirements are often not recapitulated well in animal models. Here, we have investigated the association between human GATA6 haploinsufficiency and a wide range...
6.
Wang Q, Zou Y, Nowotschin S, Kim S, Li Q, Soh C, et al.
Cell Stem Cell
. 2016 Nov;
20(1):70-86.
PMID: 27889317
In this study, we outline a regulatory network that involves the p53 tumor suppressor family and the Wnt pathway acting together with the TGF-β pathway in mesendodermal differentiation of mouse...
7.
Soh C, Huangfu D
Methods Mol Biol
. 2016 Oct;
1498:57-78.
PMID: 27709569
The recent advent of engineered nucleases including the CRISPR/Cas9 system has greatly facilitated genome manipulation in human pluripotent stem cells (hPSCs). In addition to facilitating hPSC-based disease studies, the application...
8.
Zhu Z, Li Q, Lee K, Rosen B, Gonzalez F, Soh C, et al.
Cell Stem Cell
. 2016 May;
18(6):755-768.
PMID: 27133796
Directed differentiation of human pluripotent stem cells (hPSCs) into somatic counterparts is a valuable tool for studying disease. However, examination of developmental mechanisms in hPSCs remains challenging given complex multi-factorial...
9.
Soh C, Giudice A, Jenny R, Elliott D, Hatzistavrou T, Micallef S, et al.
Stem Cell Reports
. 2014 Jun;
2(6):925-37.
PMID: 24936476
Thymic epithelial cells (TECs) play a critical role in T cell maturation and tolerance induction. The generation of TECs from in vitro differentiation of human pluripotent stem cells (PSCs) provides...
10.
Boyd R, Soh C, Boyd N, Stanley E, Chidgey A
Cell Stem Cell
. 2013 Aug;
13(2):135-6.
PMID: 23910077
Two papers in this issue of Cell Stem Cell have made a significant advance in solving one of the great challenges of modern immunology-resurrecting thymus function through the induction of...