Danwei Huangfu
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Explore the profile of Danwei Huangfu including associated specialties, affiliations and a list of published articles.
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Articles
61
Citations
4965
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Recent Articles
1.
Bisson J, Gordillo M, Kumar R, de Silva N, Yang E, Banks K, et al.
Elife
. 2025 Mar;
13.
PMID: 40080060
Haploinsufficiency for is associated with congenital heart disease (CHD) with variable comorbidity of pancreatic or diaphragm defects, although the etiology of disease is not well understood. Here, we used cardiac...
2.
Song B, Liu D, Dai W, McMyn N, Wang Q, Yang D, et al.
Nat Cell Biol
. 2025 Feb;
27(3):493-504.
PMID: 40011559
Understanding how cells respond differently to perturbation is crucial in cell biology, but existing methods often fail to accurately quantify and interpret heterogeneous single-cell responses. Here we introduce the perturbation-response...
3.
Adli M, Przybyla L, Burdett T, Burridge P, Cacheiro P, Chang H, et al.
Nature
. 2025 Feb;
638(8050):351-359.
PMID: 39939790
Recent advances in functional genomics and human cellular models have substantially enhanced our understanding of the structure and regulation of the human genome. However, our grasp of the molecular functions...
4.
Gao V, Yang R, Das A, Luo R, Luo H, McNally D, et al.
Nat Commun
. 2025 Jan;
16(1):684.
PMID: 39814735
No abstract available.
5.
Gao V, Yang R, Das A, Luo R, Luo H, McNally D, et al.
Nat Commun
. 2024 Nov;
15(1):9432.
PMID: 39487131
Identifying cell-type-specific 3D chromatin interactions between regulatory elements can help decipher gene regulation and interpret disease-associated non-coding variants. However, achieving this resolution with current 3D genomics technologies is often infeasible...
6.
Rosen B, Li Q, Cho H, Liu D, Yang D, Graff S, et al.
Nat Commun
. 2024 Oct;
15(1):8966.
PMID: 39419994
Pluripotent stem cells have remarkable self-renewal capacity: the ability to proliferate indefinitely while maintaining the pluripotent identity essential for their ability to differentiate into almost any cell type in the...
7.
Kaplan S, Wong W, Yan J, Pulecio J, Cho H, Li Q, et al.
Cell Rep
. 2024 Aug;
43(8):114640.
PMID: 39163202
Functional enhancer annotation is critical for understanding tissue-specific transcriptional regulation and prioritizing disease-associated non-coding variants. However, unbiased enhancer discovery in disease-relevant contexts remains challenging. To identify enhancers pertinent to diabetes,...
8.
Bisson J, Gordillo M, Kumar R, de Silva N, Yang E, Banks K, et al.
bioRxiv
. 2024 Jul;
PMID: 39026742
Haploinsufficiency for is associated with congenital heart disease (CHD) with variable comorbidity of pancreatic or diaphragm defects, although the etiology of disease is not well understood. Here, we used cardiac...
9.
Caspi I, Tremmel D, Pulecio J, Yang D, Liu D, Yan J, et al.
Diabetes
. 2024 May;
73(8):1336-1351.
PMID: 38775784
Article Highlights:
10.
Kaplan S, Wong W, Yan J, Pulecio J, Cho H, Li Q, et al.
bioRxiv
. 2024 May;
PMID: 38746154
Functional enhancer annotation is a valuable first step for understanding tissue-specific transcriptional regulation and prioritizing disease-associated non-coding variants for investigation. However, unbiased enhancer discovery in physiologically relevant contexts remains a...