Chetan E Chitnis
Overview
Explore the profile of Chetan E Chitnis including associated specialties, affiliations and a list of published articles.
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Articles
130
Citations
3340
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Recent Articles
1.
Kiper E, Ben Hur D, Alfandari D, Camacho A, Wani N, Efrat G, et al.
J Biol Chem
. 2025 Feb;
:108298.
PMID: 39971158
Hundreds of thousands die annually from malaria caused by Plasmodium falciparum (Pf), with the emergence of drug-resistant parasites hindering eradication efforts. Antimicrobial peptides (AMPs) are known for their ability to...
2.
Mertens J, Rigby C, Bardelli M, Quinkert D, Hou M, Diouf A, et al.
Vaccine
. 2024 May;
42(16):3621-3629.
PMID: 38704253
Recent data indicate increasing disease burden and importance of Plasmodium vivax (Pv) malaria. A robust assay will be essential for blood-stage Pv vaccine development. Results of the in vitro growth...
3.
Barrett J, Silk S, Mkindi C, Kwiatkowska K, Hou M, Lias A, et al.
Front Immunol
. 2024 Feb;
14:1193079.
PMID: 38299155
We have previously reported primary endpoints of a clinical trial testing two vaccine platforms for the delivery of malaria DBPRII: viral vectors (ChAd63, MVA), and protein/adjuvant (PvDBPII with 50µg Matrix-M™...
4.
Martinez F, White M, Guillotte-Blisnick M, Huon C, Boucharlat A, Agou F, et al.
NPJ Vaccines
. 2024 Jan;
9(1):10.
PMID: 38184681
The receptor-binding domain, region II, of the Plasmodium vivax Duffy binding protein (PvDBPII) binds the Duffy antigen on the reticulocyte surface to mediate invasion. A heterologous vaccine challenge trial recently...
5.
Bouyssou I, El Hoss S, Doderer-Lang C, Schoenhals M, Rasoloharimanana L, Vigan-Womas I, et al.
Cell Host Microbe
. 2023 Dec;
31(12):2080-2092.e5.
PMID: 38056460
Vivax malaria has long been thought to be absent from sub-Saharan Africa owing to the high proportion of individuals lacking the Duffy antigen receptor for chemokines (DARC) in their erythrocytes....
6.
Natama H, Moncunill G, Vidal M, Rouamba T, Aguilar R, Santano R, et al.
Infect Immun
. 2023 Sep;
91(10):e0026823.
PMID: 37754682
In this study, we investigated how different categories of prenatal malaria exposure (PME) influence levels of maternal antibodies in cord blood samples and the subsequent risk of malaria in early...
7.
Macalinao M, Fornace K, Reyes R, Hall T, Bareng A, Adams J, et al.
Lancet Reg Health West Pac
. 2023 Sep;
37:100792.
PMID: 37693871
Background: Assessing the status of malaria transmission in endemic areas becomes increasingly challenging as countries approach elimination. Serology can provide robust estimates of malaria transmission intensities, and multiplex serological assays...
8.
Martinez F, Guillotte-Blisnick M, Huon C, England P, Popovici J, Laude H, et al.
Sci Rep
. 2023 Aug;
13(1):13904.
PMID: 37626150
The invasion of reticulocytes by Plasmodium vivax merozoites is dependent on the interaction of the Plasmodium vivax Duffy Binding Protein (PvDBP) with the Duffy antigen receptor for chemokines (DARC). The...
9.
Hou M, Barrett J, Themistocleous Y, Rawlinson T, Diouf A, Martinez F, et al.
Sci Transl Med
. 2023 Jul;
15(704):eadf1782.
PMID: 37437014
There are no licensed vaccines against . We conducted two phase 1/2a clinical trials to assess two vaccines targeting Duffy-binding protein region II (PvDBPII). Recombinant viral vaccines using chimpanzee adenovirus...
10.
Pujol A, Brokhattingen N, Matambisso G, Mbeve H, Cistero P, Escoda A, et al.
Nat Commun
. 2023 Jul;
14(1):4004.
PMID: 37414792
Pregnant women attending first antenatal care (ANC) visits represent a promising malaria surveillance target in Sub-Saharan Africa. We assessed the spatio-temporal relationship between malaria trends at ANC (n = 6471)...