Cheri A Lee
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Explore the profile of Cheri A Lee including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
174
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Recent Articles
1.
Lee C, Hirsch V
Microbiol Spectr
. 2022 Mar;
10(2):e0047822.
PMID: 35297654
TRIM5α polymorphism in rhesus macaques (RM) limits the genetic pool of animals in which we can perform simian immunodeficiency virus (SIV) studies without first screening animals for permissive TRIM5α genotypes....
2.
Lee C, Beasley E, Sundar K, Smelkinson M, Vinton C, Deleage C, et al.
mBio
. 2020 Apr;
11(2).
PMID: 32317323
Simian immunodeficiency virus (SIV)-infected nonhuman primates can serve as a relevant model for AIDS neuropathogenesis. Current SIV-induced encephalitis (SIVE)/neurological complications of AIDS (neuroAIDS) models are generally associated with rapid progression...
3.
Hammoud D, Sinharay S, Shah S, Schreiber-Stainthorp W, Maric D, Muthusamy S, et al.
mBio
. 2019 May;
10(3).
PMID: 31138753
The exact cause of neurocognitive dysfunction in HIV-positive patients despite successful control of the infection in the periphery is not completely understood. One suggested mechanism is a vicious cycle of...
4.
Matsuda K, Riddick N, Lee C, Puryear S, Wu F, Lafont B, et al.
PLoS Pathog
. 2017 Aug;
13(8):e1006538.
PMID: 28787449
Despite effective control of plasma viremia with the use of combination antiretroviral therapies (cART), minor cognitive and motor disorders (MCMD) persist as a significant clinical problem in HIV-infected patients. Non-human...
5.
Liu X, Musser D, Lee C, Yang X, Arnold J, Cameron C, et al.
Viruses
. 2015 Oct;
7(10):5571-86.
PMID: 26516899
The Sabin I poliovirus live, attenuated vaccine strain encodes for four amino acid changes (i.e., D53N, Y73H, K250E, and T362I) in the RNA-dependent RNA polymerase (RdRp). We have previously shown...
6.
Lee C, August A, Arnold J, Cameron C
Methods Mol Biol
. 2015 Oct;
1349:83-104.
PMID: 26458831
Vaccines remain the most effective way of preventing infection and spread of infectious diseases. These prophylactics have been used for centuries but still to this day only three main design...
7.
Korboukh V, Lee C, Acevedo A, Vignuzzi M, Xiao Y, Arnold J, et al.
J Biol Chem
. 2014 Sep;
289(43):29531-44.
PMID: 25213864
The ability of an RNA virus to exist as a population of genetically distinct variants permits the virus to overcome events during infections that would otherwise limit virus multiplication or...
8.
Liu X, Yang X, Lee C, Moustafa I, Smidansky E, Lum D, et al.
J Biol Chem
. 2013 Oct;
288(45):32753-32765.
PMID: 24085299
All viral RNA-dependent RNA polymerases (RdRps) have a conserved structural element termed motif D. Studies of the RdRp from poliovirus (PV) have shown that a conformational change of motif D...
9.
Weeks S, Lee C, Zhao Y, Smidansky E, August A, Arnold J, et al.
J Biol Chem
. 2012 Aug;
287(38):31618-22.
PMID: 22854962
Live, attenuated vaccines have prevented morbidity and mortality associated with myriad viral pathogens. Development of live, attenuated vaccines has traditionally relied on empirical methods, such as growth in nonhuman cells....