Chengqi Yi
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Explore the profile of Chengqi Yi including associated specialties, affiliations and a list of published articles.
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121
Citations
7284
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Recent Articles
1.
Zhang X, Lu L, Yi C, Li X
STAR Protoc
. 2025 Feb;
6(1):103599.
PMID: 39893640
RNA 5-methylcytosine (mC) is a widespread modification and plays a crucial role in gene expression regulation. Here, we present a protocol for transcriptome-wide mC methylome profiling at base resolution using...
2.
Bai Y, Li K, Peng J, Yi C
Life Med
. 2025 Jan;
2(1):lnad008.
PMID: 39872957
To date, over 170 different kinds of chemical modifications on RNAs have been identified, some of which are involved in multiple aspects of RNA fate, ranging from RNA processing, nuclear...
3.
Xiang B, Zhang M, Li K, Zhang Z, Liu Y, Gao M, et al.
Nat Immunol
. 2025 Jan;
26(2):252-264.
PMID: 39762445
T cell-based immunotherapies have revolutionized cancer treatment, yet durable responses remain elusive. Here we show that PCIF1, an RNA N 2'-O-dimethyladenosine (mA) methyltransferase, negatively regulates CD8 T cell antitumor responses....
4.
Yang L, Ulitsky I, Gilbert W, Yi C, Ule J, Caudron-Herger M
Mol Cell
. 2024 Oct;
84(19):3567-3571.
PMID: 39366342
High-throughput sequencing methods have led to the discovery of many non-coding RNAs, RNA modifications, and protein-RNA interactions. While the list keeps growing, the challenge of determining their functions remains. For...
5.
Lu L, Zhang X, Zhou Y, Shi Z, Xie X, Zhang X, et al.
Mol Cell
. 2024 Jul;
84(15):2984-3000.e8.
PMID: 39002544
5-methylcytosine (mC) is a prevalent RNA modification crucial for gene expression regulation. However, accurate and sensitive mC sites identification remains challenging due to severe RNA degradation and reduced sequence complexity...
6.
7.
Wang Y, Yang C, Sun H, Jiang H, Zhang P, Huang Y, et al.
Genomics Proteomics Bioinformatics
. 2024 Jun;
22(4).
PMID: 38937660
The most common epigenetic modification of messenger RNAs (mRNAs) is N6-methyladenosine (m6A), which is mainly located near the 3' untranslated region of mRNAs, near the stop codons, and within internal...
8.
Li K, Peng J, Yi C
Fundam Res
. 2024 Jun;
3(5):738-748.
PMID: 38933299
More than 160 types of post-transcriptional RNA modifications have been reported; there is substantial variation in modification type, abundance, site, and function across species, tissues, and RNA type. The recent...
9.
He B, Yao H, Yi C
RSC Chem Biol
. 2024 Jun;
5(6):500-507.
PMID: 38846078
DNA cytosine methylation, a crucial epigenetic modification, involves the dynamic interplay of 5-methylcytosine (5mC) and its oxidized form, 5-hydroxymethylcytosine (5hmC), generated by ten-eleven translocation (TET) DNA dioxygenases. This process is...
10.
He B, Chen Y, Yi C
Curr Opin Genet Dev
. 2024 Jun;
87:102212.
PMID: 38823337
The epitranscriptome encompasses a diverse array of dynamic and reversible RNA modifications, affecting both coding and noncoding RNAs. Over 170 types of RNA chemical modifications have been identified, underscoring the...