Chengqi Yi
Overview
Explore the profile of Chengqi Yi including associated specialties, affiliations and a list of published articles.
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Articles
121
Citations
7284
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Recent Articles
11.
Zhang L, Yi C, Xia X, Jiang Z, Du L, Yang S, et al.
BMC Genomics
. 2024 Apr;
25(1):412.
PMID: 38671394
Background: Solanum aculeatissimum and Solanum torvum belong to the Solanum species, and they are essential plants known for their high resistance to diseases and adverse conditions. They are frequently used...
12.
Chen L, Zhu B, Ru G, Meng H, Yan Y, Hong M, et al.
Nat Biotechnol
. 2024 Apr;
42(6):987.
PMID: 38658731
No abstract available.
13.
Chen L, Zhang S, Xue N, Hong M, Zhang X, Zhang D, et al.
Nat Chem Biol
. 2024 Apr;
20(8):1094.
PMID: 38649454
No abstract available.
14.
Song J, Luo N, Dong L, Peng J, Yi C
Wiley Interdiscip Rev RNA
. 2024 Apr;
15(2):e1844.
PMID: 38576085
RNA-based therapeutics offer a flexible and reversible approach for treating genetic disorders, such as antisense oligonucleotides, RNA interference, aptamers, mRNA vaccines, and RNA editing. In recent years, significant advancements have...
15.
Yang L, Huo Y, Wang M, Zhang D, Zhang T, Wu H, et al.
Nat Chem Biol
. 2024 Mar;
20(9):1176-1187.
PMID: 38553609
Cytosine base editors (CBEs) are effective tools for introducing C-to-T base conversions, but their clinical applications are limited by off-target and bystander effects. Through structure-guided engineering of human APOBEC3A (A3A)...
16.
Zhang M, Zhang X, Ma Y, Yi C
RNA
. 2024 Mar;
30(5):537-547.
PMID: 38531648
Over the past decade, advancements in epitranscriptomics have significantly enhanced our understanding of mRNA metabolism and its role in human development and diseases. This period has witnessed breakthroughs in sequencing...
17.
Luo N, Huang Q, Dong L, Liu W, Song J, Sun H, et al.
Nat Biotechnol
. 2024 Mar;
43(1):114-123.
PMID: 38448662
Programmable RNA pseudouridylation has emerged as a new type of RNA base editor to suppress premature termination codons (PTCs) that can lead to truncated and nonfunctional proteins. However, current methods...
18.
Song J, Zhuang Y, Yi C
Nat Chem Biol
. 2024 Feb;
20(3):277-290.
PMID: 38418907
Clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editors are powerful tools in biology and hold great promise for the treatment of human diseases. Advanced DNA base editing tools, such...
19.
Bai D, Zhang X, Xiang H, Guo Z, Zhu C, Yi C
Nat Biotechnol
. 2024 Feb;
43(1):85-96.
PMID: 38336903
Dynamic 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) modifications to DNA regulate gene expression in a cell-type-specific manner and are associated with various biological processes, but the two modalities have not yet...
20.
Shen W, Sun H, Liu C, Yi Y, Hou Y, Xiao Y, et al.
Nat Protoc
. 2024 Jan;
19(4):1252-1287.
PMID: 38253658
N-methyladenosine (mA) is the most abundant posttranscriptional chemical modification in mRNA, involved in regulating various physiological and pathological processes throughout mRNA metabolism. Recently, we developed GLORI, a sequencing method that...