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Cheng E Chee

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Articles 23
Citations 949
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Recent Articles
1.
Cho B, Chiu C, Massarelli E, Buchschacher G, Goto K, Overbeck T, et al.
Lung Cancer . 2024 Jan; 188:107442. PMID: 38171156
Objectives: NTRK fusions result in constitutively active oncogenic TRK proteins responsible for ∼ 0.2 % of non-small cell lung cancer (NSCLC) cases. Approximately 40 % of patients with advanced NSCLC...
2.
Chee C, Ooi M, Lee S, Sundar R, Heong V, Yong W, et al.
Target Oncol . 2023 Apr; 18(3):391-402. PMID: 37060431
Background: Phosphatase of regenerating liver-3 (PRL-3) is involved in cellular processes driving metastasis, cell proliferation, invasion, motility and survival. It has been shown to be upregulated and overexpressed in cancer...
3.
Loh J, Wu J, Chieng J, Chan A, Yong W, Sundar R, et al.
Br J Cancer . 2023 Feb; 128(8):1514-1520. PMID: 36797357
Background: Patient selection is key in Phase I studies, and prognosis can be difficult to estimate in heavily pre-treated patients. Previous prognostic models like the Royal Marsden Hospital (RMH) score...
4.
Hashimoto A, Sarker D, Reebye V, Jarvis S, Sodergren M, Kossenkov A, et al.
Clin Cancer Res . 2021 Aug; 27(21):5961-5978. PMID: 34407972
Purpose: To evaluate the mechanisms of how therapeutic upregulation of the transcription factor, CCAAT/enhancer-binding protein alpha (C/EBPα), prevents tumor progression in patients with advanced hepatocellular carcinoma (HCC) and in different...
5.
Chan G, Chee C
Cancers (Basel) . 2020 Dec; 12(12). PMID: 33256170
The liver is the dominant site of metastasis for patients with colorectal cancer. For those with isolated liver metastases, surgical resection with systemic therapy has led to long-term remission in...
6.
Chan G, Chee C
J Gastrointest Oncol . 2020 Jan; 10(6):1183-1192. PMID: 31949938
Surgical resection is the only curative treatment for locoregional colon cancer. The goal of adjuvant chemotherapy is to eradicate micro-metastatic disease and improve survival. This has been most clearly demonstrated...
7.
Sundar R, Tan I, Chee C
J Clin Oncol . 2019 Sep; 37(33):3066-3068. PMID: 31550189
No abstract available.
8.
Chee C, Meropol N
Oncologist . 2014 May; 19(7):704-11. PMID: 24869929
The decision regarding adjuvant therapy for patients with stage II colon cancer remains a challenge. In contrast to stage III colon cancer, for which compelling clinical data support the use...
9.
Chee C, Ashrani A, Marks R, Petterson T, Bailey K, Melton 3rd L, et al.
Blood . 2014 May; 123(25):3972-8. PMID: 24782507
Active cancer is the major predictor of venous thromboembolism (VTE) recurrence, but further stratification of recurrence risk is uncertain. In a population-based cohort study of all Olmsted County, Minnesota, residents...
10.
Yang Z, Chee C, Huang S, Sinicrope F
Mol Cancer Ther . 2011 Sep; 10(9):1533-41. PMID: 21878654
Autophagy is a homeostatic, catabolic degradation process whereby cellular proteins and organelles are engulfed by autophagosomes, digested in lysosomes, and recycled to sustain cellular metabolism. Autophagy has dual roles in...