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Cheng-Po Huang

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Articles 15
Citations 337
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Recent Articles
1.
Lin T, Huang C, Au L, Chang Y, Hu C, Lin S
Chem Res Toxicol . 2012 Oct; 25(11):2340-51. PMID: 23088786
We previously reported that the anticancer activity of a botanical compound 10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone [HQ17(3)] was attributed to topoisomerase (Topo) IIα poisoning and the induction of oxidative damage. HQ17(3) irreversibly inhibits Topo...
2.
Huang C, Tsai M, Chang T, Tang W, Chen S, Lai H, et al.
Cancer Lett . 2012 Sep; 328(1):144-51. PMID: 22935675
Molecular targeting therapeutics, such as EGFR tyrosine kinase inhibitors (TKIs), are important treatment strategies for lung cancer. Currently, the major challenge confronting targeted cancer therapies is the development of resistance....
3.
Huang C, Liu Y, Nakatsuji T, Shi Y, Gallo R, Lin S, et al.
Proteomics Clin Appl . 2010 Dec; 2(9):1234-45. PMID: 21136919
Proteomics is a powerful tool for the identification of proteins, which provides a basis for rational vaccine design. However, it is still a highly technical and time-consuming task to examine...
4.
Huang C, Au L, Chiou R, Chung P, Chen S, Tang W, et al.
J Agric Food Chem . 2010 Nov; 58(23):12123-9. PMID: 21067217
The stilbenoids, arachidin-1 (Ara-1), arachidin-3, isopentadienylresveratrol, and resveratrol, have been isolated from germinating peanut kernels and characterized as antioxidant and anti-inflammatory agents. Resveratrol possesses anticancer activity, and studies have indicated...
5.
Chang T, Tsai M, Su K, Wu S, Huang C, Yu S, et al.
Am J Respir Crit Care Med . 2010 Nov; 183(8):1071-9. PMID: 21037017
Rationale: Non-small cell lung cancers carrying epidermal growth factor receptor (EGFR) mutations respond well to EGFR tyrosine kinase inhibitors (TKIs), but patients ultimately develop drug resistance and relapse. Although epithelial-mesenchymal...
6.
Chen Y, Y-Y R, Lin T, Huang C, Tang W, Chen S, et al.
J Agric Food Chem . 2009 Jan; 57(6):2200-5. PMID: 19159217
The alkylhydroquinone 10'(Z)-heptadecenylhydroquinone [HQ17(1)], isolated from the sap of the lacquer tree Rhus succedanea, was found to inhibit the activity of tyrosinase and to suppress melanin production in animal cells....
7.
Nakatsuji T, Shi Y, Zhu W, Huang C, Chen Y, Lee D, et al.
Proteomics . 2008 Jul; 8(16):3406-15. PMID: 18651708
Acne is a human disease of the sebaceous hair follicle. Unlike humans, most animals produce little or no triglycerides in hair follicles to harbor Propionibacterium acnes a fact that has...
8.
Nakatsuji T, Liu Y, Huang C, Zoubouis C, Gallo R, Huang C
J Invest Dermatol . 2008 May; 128(10):2451-7. PMID: 18463682
Propionibacterium acnes is a key pathogen involved in the progression of inflammation in acne vulgaris. We examined whether vaccination against P. acnes suppressed P. acnes-induced skin inflammation. Inactivation of P....
9.
Nakatsuji T, Liu Y, Huang C, Zouboulis C, Gallo R, Huang C
PLoS One . 2008 Feb; 3(2):e1551. PMID: 18253498
Background: Acne vulgaris afflicts more than fifty million people in the United State and the severity of this disorder is associated with the immune response to Propionibacterium acnes (P. acnes)....
10.
Huang C, Fang W, Lin L, Chiou R, Kan L, Chi N, et al.
Toxicol Appl Pharmacol . 2008 Jan; 227(3):331-8. PMID: 18164362
Cytotoxic alkyl hydroquinone compounds have been isolated from many plants. We previously isolated 3 structurally similar cytotoxic alkyl hydroquinone compounds from the sap of the lacquer tree Rhus succedanea L....