Cheng-Kun Du
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Explore the profile of Cheng-Kun Du including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
347
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Recent Articles
11.
Inagaki T, Akiyama T, Du C, Zhan D, Yoshimoto M, Shirai M
Free Radic Res
. 2016 Mar;
50(6):645-53.
PMID: 26953687
To elucidate the involvement of monoamine oxidase (MAO) in hydroxyl radical production and cardiomyocyte injury during ischemia as well as after reperfusion, we applied microdialysis technique to the heart of...
12.
Waddingham M, Edgley A, Astolfo A, Inagaki T, Fujii Y, Du C, et al.
Cardiovasc Diabetol
. 2015 Jul;
14:92.
PMID: 26194354
Background: Impaired actin-myosin cross-bridge (CB) dynamics correlate with impaired left ventricular (LV) function in early diabetic cardiomyopathy (DCM). Elevated expression and activity of Rho kinase (ROCK) contributes to the development...
13.
Du C, Zhan D, Morimoto S, Akiyama T, Schwenke D, Hosoda H, et al.
Pharmacol Res Perspect
. 2014 Dec;
2(5):e00064.
PMID: 25505608
Although ghrelin has been demonstrated to improve cardiac function in heart failure, its therapeutic efficacy on the life expectancy remains unknown. We aim to examine whether ghrelin can improve the...
14.
Du C, Zhan D, Akiyama T, Sonobe T, Inagaki T, Shirai M
Life Sci
. 2014 Oct;
117(1):33-9.
PMID: 25277944
Aims: The aim of this study was to elucidate myocardial interstitial serotonin (5-HT) kinetics in the heart, including 5-HT reuptake and enzymatic degradation to 5-hydroxyindole acetic acid (5-HIAA) via monoamine...
15.
Du C, Zhan D, Morimoto S
Life Sci
. 2014 Jun;
109(1):15-9.
PMID: 24931907
Aims: We have previously demonstrated that propyl gallate has a Ca(2+) sensitizing effect on the force generation in membrane-permeabilized (skinned) cardiac muscle fibers. However, in vivo beneficial effects of propyl...
16.
Zhan D, Du C, Akiyama T, Sonobe T, Tsuchimochi H, Shimizu S, et al.
Auton Neurosci
. 2013 Mar;
176(1-2):91-4.
PMID: 23499513
We applied a microdialysis technique to the left ventricular myocardium of anesthetized mice and tried to monitor acetylcholine (ACh) release from cardiac vagal nerves. Transection of bilateral cervical vagal nerves...
17.
Li L, Morimoto S, Take S, Zhan D, Du C, Wang Y, et al.
J Mol Cell Cardiol
. 2012 Aug;
53(6):760-7.
PMID: 22921782
Inherited or non-inherited dilated cardiomyopathy (DCM) patients develop varied disease phenotypes leading to death after developing congestive heart failure (HF) or sudden death with mild or no overt HF symptoms,...
18.
Tadano N, Du C, Yumoto F, Morimoto S, Ohta M, Xie M, et al.
Br J Pharmacol
. 2010 Oct;
161(5):1034-43.
PMID: 20977454
Background And Purpose: Catechins, biologically active polyphenols in green tea, are known to have a protective effect against cardiovascular diseases. In this study, we investigated direct actions of green tea...
19.
Wang Y, Morimoto S, Du C, Lu Q, Zhan D, Tsutsumi T, et al.
Cardiovasc Res
. 2010 May;
87(4):636-46.
PMID: 20453157
Aims: Thyroid hormone (TH) has prominent effects on the heart, and hyperthyroidism is occasionally found to be a cause of dilated cardiomyopathy (DCM). We aim to explore the potential role...
20.
Zhan D, Morimoto S, Du C, Wang Y, Lu Q, Tanaka A, et al.
Cardiovasc Res
. 2009 May;
84(1):64-71.
PMID: 19477965
Aims: Extensive clinical studies have demonstrated that beta-adrenoceptor blocking agents (beta-blockers) are beneficial in the treatment of chronic heart failure, which is due to various aetiologies, including idiopathic dilated cardiomyopathy...