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Toshiyuki Sasaguri

Explore the profile of Toshiyuki Sasaguri including associated specialties, affiliations and a list of published articles. Areas
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Articles 95
Citations 1281
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Recent Articles
1.
Arioka M, Miura K, Han R, Igawa K, Takahashi-Yanaga F, Sasaguri T
Life Sci . 2024 Jun; 351:122807. PMID: 38852800
Aims: Differentiation-inducing factor-1 (DIF-1) is a polyketide produced by Dictyostelium discoideum that inhibits growth and migration, while promoting the differentiation of Dictyostelium stalk cells through unknown mechanisms. DIF-1 localizes in...
2.
Arioka M, Seto-Tetsuo F, Inoue T, Miura K, Ishikane S, Igawa K, et al.
Life Sci . 2023 Nov; 335:122278. PMID: 37981227
Aims: Differentiation-inducing factor-1 (DIF-1), a compound in Dictyostelium discoideum, exhibits anti-cancer effects by inhibiting cell proliferation and motility of various mammalian cancer cells in vitro and in vivo. In addition,...
3.
Inoue T, Miura K, Han R, Seto-Tetsuo F, Arioka M, Igawa K, et al.
J Pharmacol Sci . 2023 Apr; 152(1):39-49. PMID: 37059490
Differentiation-inducing factor 1 (DIF-1) is a morphogen produced by Dictyostelium discoideum that inhibits the proliferation and migration of both D. discoideum and most mammalian cells. Herein, we assessed the effect...
4.
Shuto T, Yanagita T, Sasaguri T, Nishi A
Nihon Yakurigaku Zasshi . 2023 Mar; 158(2):128-133. PMID: 36858490
Pharmacology role-play works well for students playing the role of the medical doctor or patient, but students without any roles behave just like observers, resulting in a relatively low learning...
5.
Sasaguri T
Nihon Yakurigaku Zasshi . 2023 Mar; 158(2):112-118. PMID: 36858488
A variety of new methods are being tried in education of pharmacology for medical students, to make pharmacology be directly oriented to practical medical treatment. Among them, thinking that the...
6.
Yanagita T, Sasaguri T
Nihon Yakurigaku Zasshi . 2023 Mar; 158(2):111. PMID: 36858487
No abstract available.
7.
Seto-Tetsuo F, Arioka M, Miura K, Inoue T, Igawa K, Tomooka K, et al.
Int Immunopharmacol . 2023 Feb; 117:109913. PMID: 36812674
The tumor microenvironment (TME), largely composed of tumor-associated macrophages (TAMs) and cancer-associated fibroblasts (CAFs), plays a key role in cancer progression. A small molecule, differentiation-inducing factor-1 (DIF-1) secreted by Dictyostelium...
8.
Hirata A, Ishikane S, Takahashi-Yanaga F, Arioka M, Okui T, Nojiri C, et al.
Hypertens Res . 2022 Sep; 45(12):1869-1881. PMID: 36171325
Renin-angiotensin system inhibitors have been shown to prevent cancer metastasis in experimental models, but there are limited data in clinical studies. We aimed to explore whether renin-angiotensin system inhibitors administered...
9.
Takiguchi T, Takahashi-Yanaga F, Ishikane S, Tetsuo F, Hosoda H, Arioka M, et al.
Eur J Pharmacol . 2021 Aug; 909:174415. PMID: 34375673
Angiotensin II (Ang II) reportedly facilitates primary tumor growth and distal hematogenous metastasis formation in various murine intravenous metastasis models. However, it is unclear whether Ang II accelerates the initial...
10.
Seto-Tetsuo F, Arioka M, Miura K, Inoue T, Igawa K, Tomooka K, et al.
Oncogene . 2021 Jul; 40(37):5579-5589. PMID: 34304250
We have previously reported that the differentiation-inducing factor-1 (DIF-1), a compound identified in Dictyostelium discoideum, suppresses the growth of MCF-7 breast cancer cells by inactivating p70 ribosomal protein S6 kinase...