Chen Shemesh
Overview
Explore the profile of Chen Shemesh including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
166
Followers
0
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Recent Articles
1.
Twitto-Greenberg R, Liraz-Zaltsman S, Michaelson D, Liraz O, Lubitz I, Atrakchi-Baranes D, et al.
Neurobiol Aging
. 2024 Feb;
133:16-27.
PMID: 38381472
A significant progressive decline in beta-carotene (βC) levels in the brain is associated with cognitive impairment and a higher prevalence of Alzheimer's disease (AD). In this study, we investigated whether...
2.
Liraz Zaltsman S, Sharabi S, Guez D, Daniels D, Cooper I, Shemesh C, et al.
J Neurotrauma
. 2023 Sep;
41(3-4):430-446.
PMID: 37776183
The blood-brain barrier (BBB) is composed of brain microvasculature that provides selective transport of solutes from the systemic circulation into the central nervous system to protect the brain and spinal...
3.
Cooper I, Last D, Ravid O, Rand D, Matsree E, Omesi L, et al.
Fluids Barriers CNS
. 2023 Sep;
20(1):67.
PMID: 37737197
Background: Pharmacological treatment of CNS diseases is limited due to the presence of the blood-brain barrier (BBB). Recent years showed significant advancement in the field of CNS drug delivery enablers,...
4.
Cooper I, Ravid O, Rand D, Atrakchi D, Shemesh C, Bresler Y, et al.
Pharmaceutics
. 2021 Oct;
13(10).
PMID: 34683850
Human serum albumin (HSA) is efficiently taken up by cancer cells as a source of carbon and energy. In this study, we prepared a monomodified derivative of HSA covalently linked...
5.
Shelly S, Liraz Zaltsman S, Ben-Gal O, Dayan A, Ganmore I, Shemesh C, et al.
Biomaterials
. 2021 Aug;
276:121039.
PMID: 34352627
Titanium dioxide (TiO) is a frequently used biomaterial, particularly in orthopedic and dental implants, and it is considered an inert and benign compound. This has resulted in toxicological scrutiny for...
6.
Rand D, Ravid O, Atrakchi D, Israelov H, Bresler Y, Shemesh C, et al.
Pharmaceutics
. 2021 Mar;
13(3).
PMID: 33670876
The objective of this study was to investigate the molecular response to damage at the blood brain barrier (BBB) and to elucidate critical pathways that might lead to effective treatment...
7.
Friedman-Levi Y, Liraz-Zaltsman S, Shemesh C, Rosenblatt K, Kesner E, Gincberg G, et al.
Exp Neurol
. 2021 Jan;
338:113604.
PMID: 33453212
CCR5 and CXCR4 are structurally related chemokine receptors that belong to the superfamily of G-protein coupled receptors through which the HIV virus enters and infects cells. Both receptors are also...
8.
Viswanathan G, Shwartz D, Losev Y, Arad E, Shemesh C, Pichinuk E, et al.
Cell Mol Life Sci
. 2019 Sep;
77(14):2795-2813.
PMID: 31562564
Neurofibrillary tangles of the Tau protein and plaques of the amyloid β peptide are hallmarks of Alzheimer's disease (AD), which is characterized by the conversion of monomeric proteins/peptides into misfolded...
9.
Sharabi S, Bresler Y, Ravid O, Shemesh C, Atrakchi D, Schnaider-Beeri M, et al.
Drug Deliv
. 2019 Apr;
26(1):459-469.
PMID: 30957567
The blood-brain barrier (BBB) is limiting transcellular and paracellular movement of molecules and cells, controls molecular traffic, and keeps out toxins. However, this protective function is the major hurdle for...
10.
Elhaik Goldman S, Goez D, Last D, Naor S, Liraz Zaltsman S, Sharvit-Ginon I, et al.
Aging Cell
. 2018 Aug;
17(5):e12818.
PMID: 30079520
Type 2 diabetes (T2D) is associated with increased risk of Alzheimer's disease (AD). There is evidence for impaired blood-brain barrier (BBB) in both diseases, but its role in the interplay...