Charlotte Hellmich
Overview
Explore the profile of Charlotte Hellmich including associated specialties, affiliations and a list of published articles.
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24
Citations
400
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Recent Articles
11.
Moore J, Mistry J, Hellmich C, Horton R, Wojtowicz E, Jibril A, et al.
J Clin Invest
. 2022 Jan;
132(5).
PMID: 34990402
The bone marrow (BM) microenvironment regulates acute myeloid leukemia (AML) initiation, proliferation, and chemotherapy resistance. Following cancer cell death, a growing body of evidence suggests an important role for remaining...
12.
Isaacs-Ten A, Moreno-Gonzalez M, Bone C, Martens A, Bernuzzi F, Ludwig T, et al.
Cell Mol Gastroenterol Hepatol
. 2021 Dec;
13(4):1019-1039.
PMID: 34952202
Background & Aims: Inflammation is the hallmark of chronic liver disease. Metabolism is a key determinant to regulate the activation of immune cells. Here, we define the role of sirtuin...
13.
Mistry J, Hellmich C, Moore J, Jibril A, Macaulay I, Moreno-Gonzalez M, et al.
Nat Commun
. 2021 Dec;
12(1):7130.
PMID: 34880245
Acute infection is known to induce rapid expansion of hematopoietic stem cells (HSCs), but the mechanisms supporting this expansion remain incomplete. Using mouse models, we show that inducible CD36 is...
14.
Lamprinaki D, Garcia-Vello P, Marchetti R, Hellmich C, McCord K, Bowles K, et al.
Front Immunol
. 2021 Oct;
12:744184.
PMID: 34659241
is involved in the development of colorectal cancer (CRC) through innate immune cell modulation. However, the receptors of the interaction between ssp. and immune cells remain largely undetermined. Here, we...
15.
Bartsch U, Corbin L, Hellmich C, Taylor M, Easey K, Durant C, et al.
Sleep
. 2021 Jul;
44(12).
PMID: 34329479
The rs1344706 polymorphism in ZNF804A is robustly associated with schizophrenia and schizophrenia is, in turn, associated with abnormal non-rapid eye movement (NREM) sleep neurophysiology. To examine whether rs1344706 is associated...
16.
Mistry J, Hellmich C, Lambert A, Moore J, Jibril A, Collins A, et al.
Biomark Res
. 2021 May;
9(1):35.
PMID: 33985565
Acute myeloid leukemia (AML) remains an incurable malignancy despite recent advances in treatment. Recently a number of new therapies have emerged for the treatment of AML which target BCL-2 or...
17.
Hellmich C, Bowles K, Rushworth S
Haematologica
. 2020 Oct;
105(10):2350-2352.
PMID: 33054073
No abstract available.
18.
Mistry J, Moore J, Kumar P, Marlein C, Hellmich C, Pillinger G, et al.
Haematologica
. 2020 Mar;
106(2):589-592.
PMID: 32193250
No abstract available.
19.
Hellmich C, Moore J, Bowles K, Rushworth S
Front Oncol
. 2020 Mar;
10:230.
PMID: 32161723
Senescence is the irreversible arrest of cell proliferation that has now been shown to play an important role in both health and disease. With increasing age senescent cells accumulate throughout...
20.
Mistry J, Marlein C, Moore J, Hellmich C, Wojtowicz E, Smith J, et al.
Proc Natl Acad Sci U S A
. 2019 Nov;
116(49):24610-24619.
PMID: 31727843
Hematopoietic stem cells (HSCs) undergo rapid expansion in response to stress stimuli. Here we investigate the bioenergetic processes which facilitate the HSC expansion in response to infection. We find that...