Changyu Shan
Overview
Explore the profile of Changyu Shan including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
173
Followers
0
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Recent Articles
1.
Yang B, Shan C, Lv X, Song X, Zeng D, An R, et al.
J Med Chem
. 2025 Jan;
68(3):3146-3156.
PMID: 39846414
Radiopharmaceutical theranostics holds significant promise in tumor diagnosis and treatment, but suboptimal tumor uptake and retention remain a persistent limitation. We have conjugated a unique albumin binder to our previously...
2.
Yang B, Shan C, Song X, Lv X, Long Y, Zeng D, et al.
Eur J Nucl Med Mol Imaging
. 2024 May;
51(11):3334-3345.
PMID: 38787395
Purpose: The advancement of heterodimeric tracers, renowned for their high sensitivity, marks a significant trend in the development of radiotracers for cancer diagnosis. Our prior work on [Ga]Ga-HX01, a heterodimeric...
3.
Liu T, Gu J, Yuan Y, Yang Q, Zheng P, Shan C, et al.
J Transl Med
. 2022 Dec;
20(1):565.
PMID: 36474298
Background: Pharmacological modulation of cannabinoid 2 receptor (CB2R) is a promising therapeutic strategy for pulmonary fibrosis (PF). Thus, to develop CB2R selective ligands with new chemical space has attracted much...
4.
Shan C, Hui W, Li H, Wang Z, Guo C, Peng R, et al.
ChemMedChem
. 2020 Mar;
15(11):970-981.
PMID: 32207878
Resistance phenomena, especially acquired drug resistance, have been severely hampering the application of chemotherapeutics during cancer chemotherapy. Autophagy plays a role in maintaining the survival of cancer cells and might...
5.
Jie M, Wu Y, Gao M, Li X, Liu C, OuYang Q, et al.
Mol Cancer
. 2020 Mar;
19(1):56.
PMID: 32164722
Background: Aberrant expression of circular RNAs contributes to the initiation and progression of cancers, but the underlying mechanism remains elusive. Methods: RNA-seq and qRT-PCR were performed to screen differential expressed...
6.
Li H, Chen Q, Shan C, Guo C, Yang X, Chen Y, et al.
Front Mol Biosci
. 2020 Feb;
7:1.
PMID: 32039235
Discs-large (DLG) is a member that belongs to the membrane-associated guanylate kinase (MAGUK) family. The GK domain of DLGs has evolved into a protein-protein interaction module that could bind with...
7.
Ding F, Shan C, Li H, Zhang Y, Guo C, Zhou Z, et al.
Andrology
. 2020 Jan;
8(3):780-792.
PMID: 31955524
Background: Diabetes mellitus-induced erectile dysfunction is a common diabetic complication, and new therapeutics and the pathogenesis of diabetes mellitus-induced erectile dysfunction need to be investigated. Objectives: The aim was to...
8.
Shan C, Li H, Zhang Y, Li Y, Chen Y, He W
PeerJ
. 2019 Aug;
7:e7329.
PMID: 31404433
Epididymal protease inhibitor (EPPIN) that is located on the sperm surface and specific to the male reproductive system is a non-hormonal contraceptive target, since the binding of EPPIN with the...
9.
Zeng R, Shan C, Liu M, Jiang K, Ye Y, Liu T, et al.
Org Lett
. 2019 Mar;
21(7):2312-2316.
PMID: 30900459
An unexpected [4 + 1 + 1] annulation between α-bromo carbonyls and 1-azadienes, derived from 2-methylenebenzofuran-3(2 H)-ones or 2-methylenebenzo[ b]thiophene-3(2 H)-ones, has been observed in the presence of DABCO and...
10.
Li G, Shan C, Liu L, Zhou T, Zhou J, Hu X, et al.
PLoS One
. 2015 Feb;
10(2):e0117440.
PMID: 25659153
Hypoxia-inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF) play important roles in angiogenesis and tumor growth. Tanshinone IIA (T2A) is a novel antiangiogenic agent with promising antitumor effects;...