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Chang-Yi Lu

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Articles 8
Citations 154
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Recent Articles
1.
Lu C, Tsai K, Yen C, Hsieh C, Peng P, Huang S, et al.
Clin Exp Med . 2025 Mar; 25(1):83. PMID: 40085315
Hepatocellular carcinoma (HCC) is a major global health concern, being the sixth most common cancer and the third leading cause of cancer deaths worldwide. Less than 30% of HCC patients...
2.
Lu C, Lin C, Lee H, Peng P, Huang S, Chuang M, et al.
Cancers (Basel) . 2025 Mar; 17(5). PMID: 40075616
Background/objectives: The post-hepatectomy survival of patients with hepatocellular carcinoma (HCC) faces challenges due to high recurrence rates, especially early recurrence (ER). We investigated DNA methylation in HCC and developed a...
3.
Hsiao C, Lu C, Su H, Huang K
Oncology . 2024 Mar; 102(11):935-943. PMID: 38527449
Introduction: Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide. Lack of biomarkers for follow-up after treatment is a clinical challenge. DNA methylation has been proposed to be...
4.
Lu C, Hsiao C, Peng P, Huang S, Chuang M, Su H, et al.
Cancers (Basel) . 2023 Sep; 15(18). PMID: 37760434
Introduction: Alfa-fetoprotein (AFP), as the main serum tumor marker of hepatocellular carcinoma (HCC), is limited in terms of specificity and ability to predict outcomes. This study investigated the clinical utility...
5.
Xiang Q, Fu C, Lu C, Sun A, Chen Q, Qiao M
Environ Int . 2023 Aug; 179:108168. PMID: 37647704
Rice paddy soil is a hotspot of antibiotic resistance genes (ARGs) due to the application of organic fertilizers. However, the temporal dynamics of ARGs in rice paddy soil and its...
6.
Lu C, Chen S, Peng H, Kan P, Chang W, Yen C
Oncotarget . 2016 Dec; 8(4):6406-6418. PMID: 28031532
Hepatocellular carcinoma (HCC) is a highly malignant tumor with poor prognosis and high mortality. There is a dearth of effective early diagnostic tools, so liver resection surgery and liver transplantation...
7.
Lu C, Lin K, Tien M, Wu C, Uen Y, Tseng T
Genes Chromosomes Cancer . 2013 Apr; 52(7):636-43. PMID: 23580407
Hepatocellular carcinoma (HCC) is a highly malignant tumor with poor prognosis and high mortality due to a lack of effective medical treatment and apparent early stage symptoms. Understanding molecular mechanism...
8.
Lu Y, Wu C, Li H, Liu H, Lu C, Leu Y, et al.
Genes Chromosomes Cancer . 2010 Jan; 49(5):412-24. PMID: 20095042
DNA methylation plays a significant role in tumor progression. In this study, we used CpG microarray and differential methylation hybridization approaches to identify low density lipoprotein receptor-related protein 1B (LRP1B)...
9.
Wu C, Lu Y, Li H, Hsueh C, Lu C, Leu Y, et al.
Int J Cancer . 2009 Oct; 126(11):2542-52. PMID: 19824040
Aberrant DNA methylation is considered a major mechanism for silencing tumor suppressor genes in gastric cancer. We used CpG microarray and differential methylation hybridization strategies to identify potential tumor suppressor...
10.
Lu C, Hsieh S, Lu Y, Wu C, Chen L, Lo S, et al.
Genes Chromosomes Cancer . 2009 Sep; 48(12):1057-68. PMID: 19760608
Investigating aberrant DNA methylation in the cancer genome may identify genes that play an important role in tumor progression. In this study, we combined differential methylation hybridization and a CpG...