Cheng-Tao Wu
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Explore the profile of Cheng-Tao Wu including associated specialties, affiliations and a list of published articles.
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13
Citations
235
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Recent Articles
1.
Yeh Y, Doan L, Huang Z, Chu L, Shi T, Lee Y, et al.
Front Pharmacol
. 2022 Apr;
12:765553.
PMID: 35401158
COVID-19 is threatening human health worldwide but no effective treatment currently exists for this disease. Current therapeutic strategies focus on the inhibition of viral replication or using anti-inflammatory/immunomodulatory compounds to...
2.
Wu S, Wu C
Comput Biol Chem
. 2014 Dec;
53PB:292-307.
PMID: 25462336
A large challenge in the post-genomic era is to obtain the quantitatively dynamic interactive information of the important constitutes of underlying systems. The S-system is a dynamic and structurally rich...
3.
Lan S, Wu S, Zuchini R, Lin X, Su I, Tsai T, et al.
Autophagy
. 2014 Jul;
10(9):1687-9.
PMID: 25068270
Autophagy and microRNA (miRNA) are important regulators during cancer cell tumorigenesis. Impaired autophagy and high expression of the oncogenic microRNA MIR224 are prevalent in hepatocellular carcinoma (HCC); however, the relationship...
4.
Wu S, Wu C
Math Biosci
. 2013 Aug;
245(2):299-313.
PMID: 23927855
S-type biological systems (S-systems) are demonstrated to be universal approximations of continuous biological systems. S-systems are easy to be generalized to large systems. The systems are identified through data-driven identification...
5.
Lan S, Wu S, Zuchini R, Lin X, Su I, Tsai T, et al.
Hepatology
. 2013 Aug;
59(2):505-17.
PMID: 23913306
Unlabelled: In hepatocellular carcinoma (HCC), dysregulated expression of microRNA-224 (miR-224) and impaired autophagy have been reported separately. However, the relationship between them has not been explored. In this study we...
6.
Wu C, Chiou C, Chiu H, Yang U
BMC Genomics
. 2013 Jul;
14:438.
PMID: 23819653
Background: MicroRNAs are very small non-coding RNAs that interact with microRNA recognition elements (MREs) on their target messenger RNAs. Varying the concentration of a given microRNA may influence the expression...
7.
Lu C, Lin K, Tien M, Wu C, Uen Y, Tseng T
Genes Chromosomes Cancer
. 2013 Apr;
52(7):636-43.
PMID: 23580407
Hepatocellular carcinoma (HCC) is a highly malignant tumor with poor prognosis and high mortality due to a lack of effective medical treatment and apparent early stage symptoms. Understanding molecular mechanism...
8.
Wu S, Chen W, Chou C, Wu C
Math Biosci
. 2013 Mar;
243(1):81-98.
PMID: 23454229
In this study, we attempted to solve two important challenges in systems biology. First, although the Michaelis-Menten (MM) model provides local kinetic information, it is hard to generalize MM models...
9.
Wu S, Wu C, Chang J
Math Biosci
. 2013 Feb;
242(2):153-60.
PMID: 23376801
The inverse problem of identifying dynamic biological networks from their time-course response data set is a cornerstone of systems biology. Hill and Michaelis-Menten model, which is a forward approach, provides...
10.
Hung P, Chen Y, Cheng K, Chou H, Lyu P, Lu Y, et al.
Mol Biosyst
. 2011 Apr;
7(6):1990-8.
PMID: 21468429
Critical limb ischemia (CLI) is a severe obstruction of the arteries resulting from seriously decreased blood flow to the extremities, progressing to the point of pain and even skin ulcers...